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|Antigen||Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) Antibodies|
|Reactivity||Dog (Canine), Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This CDKN1B antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Product Details anti-CDKN1B AntibodyTarget Details CDKN1B Application Details Handling Images
Recognizes p27Kip1. Clone SX53G8 co-precipitates cdk4 in complex with p27Kip1 and is excellent for staining of formalin fixed tissues.
Cellular Localization: Nuclear.
|No Cross-Reactivity||Cow (Bovine)|
|Cross-Reactivity (Details)||Species reactivity (tested):Human, Mouse, Rat and Dog.|
|Plasmids, Primers & others|
Target Details CDKN1BProduct Details anti-CDKN1B Antibody Application Details Handling Images back to top
|Alternative Name||CDKN1B / KIP1 (CDKN1B Antibody Abstract)|
|Background||P27Kip1, a candidate tumor suppressor gene, functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF-beta induced G1 arrest.Synonyms: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1|
|Pathways||Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy|
Application DetailsProduct Details anti-CDKN1B Antibody Target Details CDKN1B Handling Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-CDKN1B Antibody Target Details CDKN1B Application Details Images back to top
ImagesProduct Details anti-CDKN1B Antibody Target Details CDKN1B Application Details Handling back to top