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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins

(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development. [provided by RefSeq, Jul 2008].
PPM1D Protein (AA 496-605) (GST tag) PPM1D Protein (AA 496-605) (GST tag) PPM1D Protein (AA 496-605) (GST tag) (ABIN1315910)

PPM1D Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

PPM1D Protein (AA 1-605) (GST tag) PPM1D Protein (AA 1-605) (GST tag) PPM1D Protein (AA 1-605) (GST tag) (ABIN1315909)

PPM1D Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

PPM1D Protein (AA 1-605) (His tag) PPM1D Protein (AA 1-605) (His tag) PPM1D Protein (AA 1-605) (His tag) (ABIN3086448)

Crystallography grade PPM1D Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins by Grade

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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins by Origin

Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins for a variety of species such as anti-Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D, anti-Mouse Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D. The species listed below are among those available. Click on a link to go to the corresponding products.

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins by Source

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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins by Protein Type

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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins by Application

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Popular Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315910
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315909
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3086448
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3130585
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2729806
Quantity 20 μg
Datasheet Datasheet

Aliases for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins

protein phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) Proteins
protein phosphatase 1D magnesium-dependent, delta isoform (Ppm1d) Proteins
protein phosphatase, Mg2+/Mn2+ dependent, 1D (Ppm1d) Proteins
protein phosphatase, Mg2+/Mn2+ dependent, 1Db (ppm1db) Proteins
protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog (ppm1d.L) Proteins
protein phosphatase, Mg2+/Mn2+ dependent, 1Da (ppm1da) Proteins
AV338790 Proteins
PP2C-DELTA Proteins
ppm1d Proteins
WIP1 Proteins
Wip1 Proteins
wu:fj44c08 Proteins
zgc:55836 Proteins
zgc:77316 Proteins
zgc:103518 Proteins

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