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Human Polyclonal MAGT1 Primary Antibody for WB - ABIN4893241
Shibatani, David, McCormack, Frueh, Skach: Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits. in Biochemistry 2005
evaluation of MAGT1 and AKAP13 (show AKAP13 Antibodies) expression in clinical hepatocellular carcinoma tissues by immunohistochemistry suggested that both proteins were strongly expressed in tumor tissues with significantly higher average immunoreactive scores of Remmele and Stegner (IRS (show IARS Antibodies)) than in non-tumor tissues
A 0.8 kb intronic duplication in MAGT1 and a single base pair deletion in the last exon of ATRX (show ATRX Antibodies) were identified in a family with five males demonstrating intellectual disability (ID) and unusual skin findings (e.g., generalized pruritus).
A deficiency in magnesium transporter 1 (MAGT1), an Mg(2 (show MUC7 Antibodies)+)-specific transporter, leads to the absence of a T cell antigen receptor-stimulated Mg(2 (show MUC7 Antibodies)+)flux and an attenuation of T cell activation.
Data show that gene expression of the Mg(2 (show MUC7 Antibodies)+) selective transporter MagT1 is upregulated in TRPM7 (show TRPM7 Antibodies)(-/-) cells.
identifed a novel gene that encodes a protein involved with Mg2 (show MUC7 Antibodies)+-evoked transport, MagT1; results suggest that MagT1 may provide a selective and regulated pathway for Mg2 (show MUC7 Antibodies)+ transport in epithelial cells[MagT1]
study shows that mutations in two OTase (show LNPEP Antibodies)-subunit genes, N33/TUSC3 (show TUSC3 Antibodies) and IAP (show ALPI Antibodies) result in autosomal-recessive nonsyndromic mental retardation
MagT1 is universally expressed in all tissues and its expression level is up-regulated in low extracellular Mg(2 (show MUC7 Antibodies)+). Knockdown of either MagT1 or TUSC3 (show TUSC3 Antibodies) protein significantly lowers the total and free intracellular Mg(2 (show MUC7 Antibodies)+) concentrations in cell lines.
identifed a novel gene that encodes a protein involved with Mg2 (show MCOLN1 Antibodies)+-evoked transport, MagT1; results suggest that MagT1 may provide a selective and regulated pathway for Mg2 (show MCOLN1 Antibodies)+ transport in epithelial cells[MagT1]
This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29.
, magnesium transporter protein 1
, oligosaccharyltransferase 3 homolog B