anti-Mouse (Murine) CD180 antibody for Immunocytochemistry

Recommended CD180 Antibody

Antigen
CD180 Molecule (CD180) Antibodies
  • Ly78
  • CD180
  • LY64
  • RP105
  • F630107B15
  • CD180 molecule
  • CD180 antigen
  • Cd180
  • CD180
Reactivity
Mouse (Murine)
88
27
3
2
Host
Rat
48
42
12
Clonality
Monoclonal
Conjugate
This CD180 antibody is un-conjugated
11
10
9
4
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
57
40
33
32
25
19
18
12
4
2
2
Options

Available images

Catalog No. ABIN2665573
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
-4.1125546 ABIN4350988 ELISA ICC IF IHC IHC (p) WB Rabbit Center Polyclonal 0

General

Antigen CD180 Molecule (CD180) Antibodies
Reactivity Mouse (Murine)
(88), (27), (3), (2)
Host Rat
(48), (42), (12)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD180 antibody is un-conjugated
(11), (10), (9), (4)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
(57), (40), (33), (32), (25), (19), (18), (12), (4), (2), (2)
Pubmed 5 references available
Supplier

Product Details anti-CD180 Antibody

Target Details CD180 Application Details Handling References for anti-CD180 antibody (ABIN2665573) Images
Brand LEAF™
Purification The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Clone RP-14
Isotype IgG2a kappa
Plasmids, Primers & others

Target Details CD180

Product Details anti-CD180 Antibody Application Details Handling References for anti-CD180 antibody (ABIN2665573) Images back to top
Antigen
Alternative Name CD180 (CD180 Antibody Abstract)
Background CD180 is a 105 kD type I membrane protein, also known as RP105 or Ly64. It is a member of the toll-like receptor family consisting of an extracellular leucine-rich repeat (LRR) and a short cytoplasmic tail. It is expressed on most B cells, monocytes/macrophages, and dendritic cells. CD180 associates with MD-1 to form the RP105/MD-1 surface receptor. CD180/MD-1, by working in concert with TLR4, controls B cell recognition and signalling of bacterial LPS. The ligation of RP105 by RP/14 leads to a strong B cell proliferative response, as well as protection from apoptosis induced by radiation or dexamethasone. Interestingly, in some systems, ligation of RP105 leads to Fas-independent apoptosis.
Pathways Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Application Details

Product Details anti-CD180 Antibody Target Details CD180 Handling References for anti-CD180 antibody (ABIN2665573) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD180 Antibody Target Details CD180 Application Details References for anti-CD180 antibody (ABIN2665573) Images back to top
Concentration 1.0 mg/mL
Preservative Azide free
Handling Advice This LEAF™ solution contains no preservative, handle under aseptic conditions
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD180 antibody (ABIN2665573)

Product Details anti-CD180 Antibody Target Details CD180 Application Details Handling Images back to top
Background publications

Chan, Mecklenbräuker, Su, Texido, Leitges, Carsetti, Lowell, Rajewsky, Miyake, Tarakhovsky: "The molecular mechanism of B cell activation by toll-like receptor protein RP-105." in: The Journal of experimental medicine, Vol. 188, Issue 1, pp. 93-101, 1998

Miyake, Shimazu, Kondo, Niki, Akashi, Ogata, Yamashita, Miura, Kimoto: "Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 3, pp. 1348-53, 1998

Yamashita, Miyake, Miura, Kaneko, Yagita, Suda, Nagata, Nomura, Sakaguchi, Kimoto: "Activation mediated by RP105 but not CD40 makes normal B cells susceptible to anti-IgM-induced apoptosis: a role for Fc receptor coligation." in: The Journal of experimental medicine, Vol. 184, Issue 1, pp. 113-20, 1996

Miyake, Yamashita, Ogata, Sudo, Kimoto: "RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 7, pp. 3333-40, 1995

Miyake, Yamashita, Hitoshi, Takatsu, Kimoto: "Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule: unresponsiveness of X-linked immunodeficient B cells." in: The Journal of experimental medicine, Vol. 180, Issue 4, pp. 1217-24, 1994

Images

Product Details anti-CD180 Antibody Target Details CD180 Application Details Handling References for anti-CD180 antibody (ABIN2665573) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD180 Molecule (CD180) antibody (ABIN2665573) anti-CD180 Molecule (CD180) antibody