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|Antigen||Fibronectin 1 (FN1) Antibodies|
|Reactivity||Chicken, Human, Mouse (Murine) Alternatives|
|Conjugate||This Fibronectin 1 antibody is un-conjugated Alternatives|
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|16 references available|
Product Details anti-Fibronectin 1 AntibodyTarget Details Fibronectin 1 Application Details Handling References for anti-Fibronectin 1 antibody (ABIN3043242) Images
|Purpose||Mouse IgG monoclonal antibody for Fibronectin, fibronectin 1 (FN1 ) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,mouse,chicken. No cross reactivity with other proteins.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Mouse IgG monoclonal antibody for Fibronectin, fibronectin 1 (FN1 ) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,mouse,chicken.
Gene Name: fibronectin 1
Protein Name: Fibronectin
|Immunogen||Fibronectin from human plasma.|
|Plasmids, Primers & others|
Target Details Fibronectin 1Product Details anti-Fibronectin 1 Antibody Application Details Handling References for anti-Fibronectin 1 antibody (ABIN3043242) Images back to top
|Alternative Name||FN1 (FN1 Antibody Abstract)|
Fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. Cellular fibronectin is a 550KDa glycoprotein existing as two heterodimers, different from plasma fibronectin in the presence of additional polypeptide segments and in altering morphology of transformed cells and hemaglutination.
|Gene ID||2335, 14268, 25661|
|UniProt||P02751, P11276, P04937|
|Pathways||Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy|
Application DetailsProduct Details anti-Fibronectin 1 Antibody Target Details Fibronectin 1 Handling References for anti-Fibronectin 1 antibody (ABIN3043242) Images back to top
WB: Concentration: 1-2 μg/mL, Species: Human, chicken, mouse
IHC-P: Concentration: 1-2 μg/mL, Species: Human, chicken, mouse
IHC-F: Concentration: 1-2 μg/mL, Species: Human, chicken, mouse
ICC: Concentration: 1 μg/mL, Species: Human, chicken, mouse
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921123 in WB, supported by ABIN921230 in IHC(P), IHC(F) and ICC.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Fibronectin 1 Antibody Target Details Fibronectin 1 Application Details References for anti-Fibronectin 1 antibody (ABIN3043242) Images back to top
|Reconstitution||Add 1 mL of PBS buffer will yield a concentration of 100 μg/mL.|
|Buffer||Mouse ascites fluid, 1.2 % sodium acetate, 2 mg BSA, with 0.01 mg Sodium azide as preservative.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
|Expiry Date||12 months|
References for anti-Fibronectin 1 antibody (ABIN3043242)Product Details anti-Fibronectin 1 Antibody Target Details Fibronectin 1 Application Details Handling Images back to top
|Product cited in:||
Wu, Wang, Ji, Ou, Xia, Zhang, Zhao: "C4orf7 modulates osteogenesis and adipogenesis of human periodontal ligament cells." in: American journal of translational research, Vol. 9, Issue 12, pp. 5708-5718, 2017
Zhang, Teng, Liu, Zhang, Liu: "Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 16, 2015
Wu, Chen, Guo, He, Hu: "Effects of transforming growth factor-?2 on myocilin expression and secretion in human primary cultured trabecular meshwork cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 8, pp. 4827-36, 2014
Gong, Liu, Ding, Liu, Li, Zheng, Jia, Zhou, Zou, Li, Huang, Fan: "Physiological pulsatile flow culture conditions to generate functional endothelium on a sulfated silk fibroin nanofibrous scaffold." in: Biomaterials, Vol. 35, Issue 17, pp. 4782-91, 2014
Gai, Lu, Tu, Liang, Zheng: "Caveolin-1 is up-regulated by GLI1 and contributes to GLI1-driven EMT in hepatocellular carcinoma." in: PLoS ONE, Vol. 9, Issue 1, pp. e84551, 2014
Shi, Shen, Liu, Huang, Jiao: "Retinoic acid receptor ? (Rarg) and nuclear receptor subfamily 5, group A, member 2 (Nr5a2) promote conversion of fibroblasts to functional neurons." in: The Journal of biological chemistry, Vol. 289, Issue 10, pp. 6415-28, 2014
Cheng, Wang, Kang, Hu, Gao, Pan: "In vitro culture of tumour-derived hepatocytes in decellularised whole-liver biological scaffolds." in: Digestion, Vol. 87, Issue 3, pp. 189-95, 2013
Sasaki, Inoue, Katada, Taguchi: "Promotion of initial cell adhesion on trisuccinimidyl citrate-modified nickel-free high-nitrogen stainless steel." in: Journal of materials science. Materials in medicine, Vol. 24, Issue 4, pp. 951-8, 2013
Wang, Wang, Zhou, Li, Zhang, Wang, Zhang, Bu, Cai, Du: "Epithelial-mesenchymal transition (EMT) induced by TNF-? requires AKT/GSK-3?-mediated stabilization of snail in colorectal cancer." in: PLoS ONE, Vol. 8, Issue 2, pp. e56664, 2013
Guo, Zeng, Zhang, Zhang, Li, Wu, Guan, Liu, Zhang, Li, Wan: "Extracellular matrix of mechanically stretched cardiac fibroblasts improves viability and metabolic activity of ventricular cells." in: International journal of medical sciences, Vol. 10, Issue 13, pp. 1837-45, 2013
Yang, Gao, Wang, Su, Xing: "Total Flavonoids of Fructus Chorspondiatis inhibits collagen synthesis of cultured rat cardiac fibroblasts induced by angiotensin II: correlated with NO/cGMP signaling pathway." in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 47, Issue 1, pp. 75-83, 2012
Zhang, Chen, Qi, Wang, Xiao, Zhu: "Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion." in: Journal of cardiovascular pharmacology, Vol. 55, Issue 1, pp. 96-105, 2010
Xia, Cheung, Sze, Lu, Jiang, Yao, Bian, Poon, Kung, Lin: "miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling." in: The Journal of biological chemistry, Vol. 285, Issue 47, pp. 36995-7004, 2010
Xiao, Ji, Li, Song, Su, Chen: "Interleukin-1? inhibits collagen synthesis and promotes its decomposition in cultured cardiac fibroblasts." in: Sheng li xue bao : [Acta physiologica Sinica], Vol. 60, Issue 3, pp. 355-61, 2008
Xue, Zhang, Liu, Wang: "A new ATP-sensitive potassium channel opener protects the kidney from hypertensive damage in spontaneously hypertensive rats." in: The Journal of pharmacology and experimental therapeutics, Vol. 315, Issue 2, pp. 501-9, 2005
Fu, Liu, Zhou, Zhou, Sun, Luo, Zhang, Xu: "Expansive effects of aorta-gonad-mesonephros-derived stromal cells on hematopoietic stem cells from embryonic stem cells." in: Chinese medical journal, Vol. 118, Issue 23, pp. 1979-86, 2005