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Human Polyclonal GSTP1 Primary Antibody for IHC, ELISA - ABIN1002398
Smeyne, Boyd, Raviie Shepherd, Jiao, Pond, Hatler, Wolf, Henderson, Smeyne: GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism. in Proceedings of the National Academy of Sciences of the United States of America 2007
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Human Polyclonal GSTP1 Primary Antibody for IF (p), IHC (p) - ABIN749858
Zhang, Chen, Liu, Qiu, Wang, Li, Wang: Up-regulation of protein tyrosine nitration in methamphetamine-induced neurotoxicity through DDAH/ADMA/NOS pathway. in Neurochemistry international 2013
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Human Polyclonal GSTP1 Primary Antibody for FACS, IF - ABIN1881393
Cho, Eom, Kim, Kim, Lee, Kong: Glutathione-S-transferase genotypes influence the risk of chemotherapy-related toxicities and prognosis in Korean patients with diffuse large B-cell lymphoma. in Cancer genetics and cytogenetics 2010
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Human Monoclonal GSTP1 Primary Antibody for IHC, ELISA - ABIN966240
Satoh, Itoh, Yamamoto, Tanaka, Hayakari, Ookawa, Yamazaki, Sato, Tsuchida, Hatayama: Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells. in Carcinogenesis 2002
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Human Monoclonal GSTP1 Primary Antibody for IF, IP - ABIN561164
Kan, Wen, Pasquier, Jankowski, Chang, Richards, Kavallaris, MacKenzie: Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization. in Oncogene 2012
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Human Monoclonal GSTP1 Primary Antibody for ICC, FACS - ABIN3072907
Lin, Nelson: Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells. in Cancer research 2003
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Human Polyclonal GSTP1 Primary Antibody for ICC, IF - ABIN449066
Lin, Yeh, Kuo, Lee, Yen, Wang, Wu, Yang, Wu: Sulforaphane potentiates the efficacy of imatinib against chronic leukemia cancer stem cells through enhanced abrogation of Wnt/β-catenin function. in Journal of agricultural and food chemistry 2012
Human Polyclonal GSTP1 Primary Antibody for ICC, IF - ABIN4314724
Ruckhäberle, Karn, Hanker, Schwarz, Schulz-Knappe, Kuhn, Böhm, Selzer, Erhard, Engels, Holtrich, Kaufmann, Rody: Breast Cancer Proteomics - Differences in Protein Expression between Estrogen Receptor-Positive and -Negative Tumors Identified by Tandem Mass Tag Technology. in Breast care (Basel, Switzerland) 2012
Human Polyclonal GSTP1 Primary Antibody for ICC, IF - ABIN4314725
Pellacani, Kestoras, Droop, Frame, Berry, Lawrence, Stower, Simms, Mann, Collins, Risbridger, Maitland: DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation. in Cell death and differentiation 2014
Human Monoclonal GSTP1 Primary Antibody for ICC, FACS - ABIN258768
Hasenfuss, Bakiri, Thomsen, Hamacher, Wagner: Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism. in Hepatology (Baltimore, Md.) 2013
Individuals with ASD (show ARSD Antibodies) (autism spectrum disorder)showed a significant diminished level of reduced glutathione, however, the distribution of GSTT1 (show GSTT1 Antibodies), GSTM1 (show GSTM1 Antibodies), and GSTP1 polymorphisms was not found to be associated with autism in this study population.
CML (show BCR Antibodies) patients with carriage of heterozygous and homozygous variant genotypes of GSTP1 Ile105Val and GSTT1 (show GSTT1 Antibodies) null, have a higher risk for development of resistance to IM.
No significant differences in allelic or genotypic frequencies of GPX1 (show GPX1 Antibodies) rs1050450 or GSTP1 rs1695 were detected between Chinese schizophrenia cases and controls.
the GSTP1 Ile105Val polymorphism is not associated with the development of gynecological cancer (meta-analysis).
DNA sequencing was performed for six single-nucleotide polymorphisms in the GSTP1, RAD51 (show RAD51 Antibodies), XRCC1 (show XRCC1 Antibodies) and XRCC3 (show XRCC3 Antibodies) genes in BC patients and the control group. Two variants in the 5'-UTR (show UTS2R Antibodies) of the XRCC3 (show XRCC3 Antibodies) and RAD51 (show RAD51 Antibodies) genes showed a significant association with susceptibility to breast cancer. Additionally, authors reported 2 mutations in intron 7 of the XRCC3 (show XRCC3 Antibodies) gene.
The SNPs in CYP1A1 (show CYP1A1 Antibodies), GSTP1 and XRCC1 (show XRCC1 Antibodies) genes did not show significant association with complete remission (CR) rate, overall survival (OS) or event free survival (EFS (show EFS Antibodies)). However, XRCC1 (show XRCC1 Antibodies) Arg194Trp SNP was associated with higher drug toxicity; carriers of variant genotypes (CT and TT) had a significantly higher frequency of myelosuppression compared to those with the wild CC genotype
There were significant differences in GSTP1 (rs1138272 and rs1695) genotype or allele frequencies between the infertile and fertile groups and synergy effects of GSTP1 and NAT2 (show SLC38A1 Antibodies) polymorphisms might lead to significant increase of infertility risk.
Significantly higher frequency of the GSTP1 polymorphism was observed in Extremely Low Birth Weight Preterm Infants with Bronchopulmonary Dysplasia.
Polymorphisms of GSTP1 rs1695 and ABCC2 (show ABCC2 Antibodies) rs717620 can be used to predict the outcomes of Uygur patients with advanced NSCLC who have received platinum-based chemotherapy. Kaplan-Meier survival analysis indicated that survival with GSTP1 AG+ GG was significantly longer than in patients with AA gene (P<0.05), and survival with ABCC2 (show ABCC2 Antibodies) CT + TT was significantly longer than in patients with CC gene.
GSTpi inhibited p38MAPK phosphorylation by directly binding p38 and influenced downstream substrate HSP27-induced actin remodeling.
Expression of both wild-type and catalytically-inactive Y7F mutant GSTP significantly attenuated LPS (show TLR4 Antibodies)- or IKKbeta (show IKBKB Antibodies)-induced production of GM-CSF (show CSF2 Antibodies). These studies indicate a complex role for GSTP in modulating NF-kappaB (show NFKB1 Antibodies), which may involve S-glutathionylation of IKK (show CHUK Antibodies) proteins, and interaction with NF-kappaB (show NFKB1 Antibodies) family members.
GSTP can exert redox regulation in the oxidative ER environment and indicate that, within the ER, GSTP influences the cellular consequences of the UPR through S-glutathionylation of a series of key interrelated proteins. Antioxid.
our study reveals the novel role of GSTP1 in regulation of iNOS (show NOS2 Antibodies) by affecting S-nitrosylation, dimerization, and stability.
These observed differences contribute to our understanding of how genetic ablation of GSTP causes different levels of myeloproliferation and migration [corrected]
GSTP1/2 are a critical regulators of hepatocyte proliferation in the initial phases of liver regeneration.
GSTP1 expression in retina increases with developmental age in mice and accompanies murine retinal maturation.
GSTP knock-out mice display decreased ubiquitination capacity and overall increased susceptibility to oxidative stress.
Report increased GSTP1 in airways of asthmatic mice.
DNIC storage function of GST P1-1 and ability of MRP1 (show ABCC1 Antibodies) to efflux DNICs are vital in protection against NO cytotoxicity
Gst-pi expression of the prostate cancers are dependent on metastatic site.
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
, deafness, X-linked 7
, fatty acid ethyl ester synthase III
, glutathione S-transferase P
, GST 7-7
, Glutathione-S-transferase placental enzyme pi type
, Glutathione-S-transferase, placental enzyme pi type
, chain 7
, glutathione S-transferase pi 2
, glutathione S-transferase, pi 2
, glutathione-S-transferase, pi 1
, Glutathione S-transferase P
, GST-pi enzyme
, glutathione S-transferase P 1
, GST YF-YF
, Gst p-1
, gst P1
, preadipocyte growth factor