Browse our anti-MTA2 (MTA2) Antibodies

Full name:: anti-Metastasis Associated 1 Family, Member 2 Antibodies (MTA2)

On www.antibodies-online.com are 119 Metastasis Associated 1 Family, Member 2 (MTA2) Antibodies from 26 different suppliers available. Additionally we are shipping MTA2 Kits (10) and MTA2 Proteins (6) and many more products for this protein. A total of 145 MTA2 products are currently listed.

Synonyms:: AW550797, DKFZp470E0911, fd61b05, Mata1l1, mmta2, Mta1l1, MTA2, pid, wu:fd61b05, wu:fi29g02, zgc:63487

list all antibodies	Gene Name	GeneID	UniProt
	MTA2	9219	O94776
	MTA2	361724
	MTA2	23942	Q9R190
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Most Popular Reactivities for anti-MTA2 (MTA2) Antibodies

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anti-Mouse (Murine) MTA2 Antibodies:

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Relevant Pathways for anti-MTA2 Antibodies

Chromatin Binding

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Top referenced anti-MTA2 Antibodies

Human Polyclonal MTA2 Primary Antibody for ICC, IF - ABIN252449 : Errico, Aze, Costanzo: Mta2 promotes Tipin-dependent maintenance of replication fork integrity. in Cell cycle (Georgetown, Tex.) 2014 (PubMed)
Cow (Bovine) Polyclonal MTA2 Primary Antibody for IHC, WB - ABIN2781484 : Schiene-Fischer, Yu: Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerases. in FEBS letters 2001 (PubMed)
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More Antibodies against MTA2 Interaction Partners

Human Metastasis Associated 1 Family, Member 2 (MTA2) interaction partners

This study is the first to demonstrate that SNHG5 is a critical and powerful regulator that is involved in GC progression through trapping MTA2 in the cytosol.
Taken together with previous findings this suggests, that MTA (show DNMT1 Antibodies)-RBBP is a stable complex, with a central role in the initial assembly of the human NuRD complex.
Authors identify non-canonical nuclear factor-kappaB (NF-kappaB (show NFKB1 Antibodies)) signaling up regulated and it was directly linked with the tumor necrosis with MT2A (show MT2 Antibodies) and pFADD genes. pFADD with MT2A (show MT2 Antibodies) can inhibit the apoptosis and promote proliferation, of colorectal cancer cells.
These results indicated there might be a tight correlation among MTA2, Ki-67 (show MKI67 Antibodies) and hepatocellular carcinoma prognosis
MTA2 is a crucial biomarker that is closely related with prognosis of colorectal carcinoma and also a potential molecular target for evaluating the prognosis and treatment of CRC (show CALR Antibodies).
MTA2 overexpression enhances colony formation and tumor growth of gastric cancer cells, but not plays important role in cancer cell migration and metastasis. IL-11 (show IL11 Antibodies) is one of the downstream effectors of MTA2 in regulating gastric cancer cells growth
MTA-2 protein may facilitate the invasive potential of non-small-cell lung cancer cells through the inhibition of the cell adhesion molecule (show MCAM Antibodies) Ep-CAM (show EPCAM Antibodies) and E-cadherin (show CDH1 Antibodies), suggesting that it might be a potential therapeutic target in NSCLC.
High MTA2 protein and mRNA expression is associated with glioma.
MTA2 acts as a central hub for cytoskeletal organization and transcription and provides a link between nuclear and cytoskeletal organization.
MTA2 depletion could significantly inhibit human breast cancer cell growth and metastasis, implying that MTA2 might be involved in the progression of breast cancer.

Mouse (Murine) Metastasis Associated 1 Family, Member 2 (MTA2) interaction partners

results in MTA2 recruitment to the Stc2 promoter, concomitant with agonist-specific epigenetic modifications targeting histone H4 lysine acetylation
Mta2 expression is up-regulated during testicular Sertoli cells phagocytosis.
Sertoli cell-specific expression of MTA2 is required for transcriptional regulation of FSHR (show FSHR Antibodies) gene during spermatogenesis.
investigation of expression/role of Mta2 in zygote/blastocyst development: Mta2 appears to be only Mta (show DNMT1 Antibodies) expressed in zygotes; Mta2 appears to control transcription/expression of H19 (show NCKAP1 Antibodies) and Peg3 (show PEG3 Antibodies) in blastocysts; Mta2 may be involved in genetic imprinting
results suggest that GATA-3 (show GATA3 Antibodies) interacts with MTA-2 to co-ordinately regulate Th2 cytokine and ifng (show IFNG Antibodies) loci during T helper cell differentiation.
Assignment of the metastasis-associated gene (Mta1 (show MTA1 Antibodies)) to mouse chromosome band 12F and the metastasis-associated gene 2 (show MAG Antibodies) (Mta2) to mouse chromosome band 19B by fluorescence in situ hybridization
These results demonstrate the importance of FOG-2 (show ZFPM2 Antibodies)/MTA (show DNMT1 Antibodies)/RbAp interactions for FOG-2 (show ZFPM2 Antibodies)-mediated transcriptional repression and further define the molecular interactions between the FOG (show APAF1 Antibodies) repression motif and the NuRD complex.
Mta2/NuRD is involved in modulating IL-4 (show IL4 Antibodies) and IFN-gamma (show IFNG Antibodies) expression in T cell immune responses

MTA2 Antigen Profile

Antigen Summary

This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.

Alternative names and synonyms associated with MTA2

metastasis associated 1 family member 2 (MTA2) antibody
metastasis associated 1 family, member 2 (mta2) antibody
metastasis associated 1 family, member 2 (Mta2) antibody
metastasis associated 1 family member 2 (mta2) antibody
metastasis-associated gene family, member 2 (Mta2) antibody
metastasis associated 1 family member 2 L homeolog (mta2.L) antibody
metastasis associated 1 family member 2 (Mta2) antibody

AW550797 antibody
DKFZp470E0911 antibody
fd61b05 antibody
Mata1l1 antibody
mmta2 antibody
Mta1l1 antibody
MTA2 antibody
pid antibody
wu:fd61b05 antibody
wu:fi29g02 antibody
zgc:63487 antibody

Protein level used designations for MTA2

MTA1-L1 protein , metastasis -associated gene 1-like 1 , metastasis associated gene family, member 2 , metastasis-associated 1-like 1 , metastasis-associated protein 2 , metastasis-associated protein MTA2 , p53 target protein in deacetylase complex , metastais-associated gene family, member 2 , metastasis-associated gene family, member 2 , metastasis associated 1 family, member 2 , metastasis-associated protein MTA2-like , metastasis associated 1-like 1 , metastasis associated 1-like protein

GENE ID	SPECIES
9219	Homo sapiens
326078	Danio rerio
361724	Rattus norvegicus
451255	Pan troglodytes
476057	Canis lupus familiaris
515389	Bos taurus
100126057	Xenopus (Silurana) tropicalis
100174093	Pongo abelii
100393564	Callithrix jacchus
100467866	Ailuropoda melanoleuca
100604491	Nomascus leucogenys
23942	Mus musculus
399148	Xenopus laevis
100732932	Cavia porcellus
100861363	Capra hircus
100063490	Equus caballus
100351042	Oryctolagus cuniculus

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Show all anti-Metastasis Associated 1 Family, Member 2 (MTA2) Antibodies with Pubmed References

Human Metastasis Associated 1 Family, Member 2 (MTA2) interaction partners

Mouse (Murine) Metastasis Associated 1 Family, Member 2 (MTA2) interaction partners

Antigen Summary

Alternative names and synonyms associated with MTA2

Protein level used designations for MTA2