anti-Human C1QB antibody for Immunohistochemistry

Recommended C1QB Antibody (supplied by: Log in to see )

Antigen
Complement Component 1, Q Subcomponent, B Chain (C1QB) Antibodies
  • complement C1q B chain
  • complement component 1, q subcomponent, beta polypeptide
  • C1QB
  • C1qb
Epitope
C-Term
11
10
7
4
2
2
2
2
2
1
1
1
1
1
Reactivity
Dog (Canine), Horse (Equine), Human
58
10
9
2
2
2
2
2
1
1
Host
Rabbit
56
2
Clonality
Polyclonal
Conjugate
This C1QB antibody is un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
56
28
14
9
8
5
2
2
1
1
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Catalog No. ABIN2773842
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.404079 ABIN6260363 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
8.404079 ABIN634558 IHC WB Rabbit C-Term Log in to see Polyclonal 0
8.404079 ABIN4286273 IHC Rabbit IgG Log in to see Polyclonal 0
1 ABIN320873 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN1876527 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2462806 IHC ELISA WB Rabbit Log in to see Polyclonal 0
1 ABIN4892067 IHC IHC (p) WB Rabbit C-Term, Isoform B Log in to see Polyclonal 0
1 ABIN2881019 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2694683 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN5915520 ELISA IF/ICC IHC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN6093994 ELISA IHC Rabbit IgG AA 104-253 Log in to see Polyclonal 0
1 ABIN6100981 ELISA IF/ICC IHC WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN6030046 IF/ICC IHC IP WB Rabbit Log in to see Polyclonal 0
1 ABIN5915517 ELISA IHC WB Rabbit Log in to see Polyclonal 0

General

Antigen Complement Component 1, Q Subcomponent, B Chain (C1QB) Antibodies
Epitope C-Term
(11), (10), (7), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Horse (Equine), Human
(58), (10), (9), (2), (2), (2), (2), (2), (1), (1)
Host Rabbit
(56), (2)
Clonality
Polyclonal
Conjugate This C1QB antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(56), (28), (14), (9), (8), (5), (2), (2), (1), (1)
Pubmed 7 references available
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Product Details anti-C1QB Antibody

Target Details C1QB Application Details Handling References for anti-C1QB antibody (ABIN2773842) Images
Blocking Peptide Blocking peptide for this product available: ABIN974149
Sequence AYNTFQVTTG GMVLKLEQGE NVFLQATDKN SLLGMEGANS IFSGFLLFPD
Predicted Reactivity Dog: 92%, Horse: 82%, Human: 100%
Characteristics This is a rabbit polyclonal antibody against C1QB. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human C1QB
Plasmids, Primers & others

Target Details C1QB

Product Details anti-C1QB Antibody Application Details Handling References for anti-C1QB antibody (ABIN2773842) Images back to top
Antigen
Alternative Name C1QB (C1QB Antibody Abstract)
Background C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB is the B-chain polypeptide of human complement subcomponent C1q.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q.
Alias Symbols: -
Protein Interaction Partner: IL32, EED, FN1, EDA2R, RELA, MYOC, PTX3, C1R, HRG, DEFA1, C1QC, C1QA,
Protein Size: 253
Molecular Weight 27 kDa
Gene ID 713
NCBI Accession NM_000491, NP_000482
UniProt P02746
Pathways Complement System

Application Details

Product Details anti-C1QB Antibody Target Details C1QB Handling References for anti-C1QB antibody (ABIN2773842) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 253 AA

Restrictions For Research Use only

Handling

Product Details anti-C1QB Antibody Target Details C1QB Application Details References for anti-C1QB antibody (ABIN2773842) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-C1QB antibody (ABIN2773842)

Product Details anti-C1QB Antibody Target Details C1QB Application Details Handling Images back to top
Product cited in:

Takamori, Atsuta, Nakamura, Sawase, Koyano, Hara: "Histopathological comparison of the onset of peri-implantitis and periodontitis in rats." in: Clinical oral implants research, Vol. 28, Issue 2, pp. 163-170, 2016

Noguchi, Ukai, Kuramoto, Yoshinaga, Nakamura, Takamori, Yamashita, Hara: "The histopathological comparison on the destruction of the periodontal tissue between normal junctional epithelium and long junctional epithelium." in: Journal of periodontal research, Vol. 52, Issue 1, pp. 74-82, 2016

Nakatsu, Yoshinaga, Kuramoto, Nagano, Ichimura, Oshino, Yoshimura, Yano, Hara: "Occlusal trauma accelerates attachment loss at the onset of experimental periodontitis in rats." in: Journal of periodontal research, Vol. 49, Issue 3, pp. 314-22, 2014

Nagano, Kaneko, Yoshinaga, Ukai, Kuramoto, Nakatsu, Oshino, Ichimura, Hara: "Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction." in: Journal of periodontal research, Vol. 48, Issue 4, pp. 420-7, 2013

Kuramoto, Yoshinaga, Kaneko, Ukai, Shiraishi, Oshino, Ichimura, Hara: "The formation of immune complexes is involved in the acute phase of periodontal destruction in rats." in: Journal of periodontal research, Vol. 47, Issue 4, pp. 455-62, 2012

Yoshinaga, Ukai, Kaneko, Nakatsu, Shiraishi, Kuramoto, Oshino, Ichimura, Hara: "Topical application of lipopolysaccharide into gingival sulcus promotes periodontal destruction in rats immunized with lipopolysaccharide." in: Journal of periodontal research, Vol. 47, Issue 5, pp. 674-80, 2012

Background publications

Roumenina, Ruseva, Zlatarova, Ghai, Kolev, Olova, Gadjeva, Agrawal, Bottazzi, Mantovani, Reid, Kishore, Kojouharova: "Interaction of C1q with IgG1, C-reactive protein and pentraxin 3: mutational studies using recombinant globular head modules of human C1q A, B, and C chains." in: Biochemistry, Vol. 45, Issue 13, pp. 4093-104, 2006

Images

Product Details anti-C1QB Antibody Target Details C1QB Application Details Handling References for anti-C1QB antibody (ABIN2773842) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibody (ABIN2773842) anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibody
Immunohistochemistry (IHC) image for anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibody (ABIN2773842) Human Muscle
Western Blotting (WB) image for anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibody (ABIN2773842) WB Suggested Anti-C1QB Antibody Titration: 0.5ug/ml Positive Control: Jurkat cell ...