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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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3.2536025 | ABIN4299962 | IHC IHC (p) SimWes WB | Rabbit | IgG | Log in to see | Polyclonal | 4 | |||
3.2536025 | ABIN4299964 | IHC IHC (p) WB | Rabbit | IgG | Center | Log in to see | Polyclonal | 0 | ||
3.2536025 | ABIN1871801 | IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
3.2536025 | ABIN1858377 | ICC IHC WB | Rabbit | IgG | AA 34-159 | Log in to see | Polyclonal | 0 | ||
3.2536025 | ABIN1858376 | ICC IHC WB | Rabbit | IgG | AA 34-159 | Log in to see | Polyclonal | 0 | ||
3.2536025 | ABIN1858374 | ICC IHC WB | Rabbit | IgG | AA 476-592 | Log in to see | Polyclonal | 0 | ||
3.2536025 | ABIN1175363 | ICC IHC WB | Rabbit | IgG | AA 269-382 | Log in to see | Polyclonal | 0 | ||
1 | ABIN1386781 | IF (p) IHC (p) WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN5514558 | WB | Rabbit | N-Term | Log in to see | Polyclonal | 0 | |||
1 | ABIN1415523 | IHC (p) WB | HRP | Rabbit | IgG | Log in to see | Polyclonal | 0 | ||
1 | ABIN1397650 | IHC (p) WB | Biotin | Rabbit | IgG | Log in to see | Polyclonal | 0 | ||
1 | ABIN2237107 | IC IHC ELISA WB | Rabbit | IgG | AA 34-159 | Log in to see | Polyclonal | 0 | ||
1 | ABIN2619139 | ELISA WB | Biotin | Rabbit | IgG | AA 34-159 | Log in to see | Polyclonal | 0 | |
1 | ABIN2619141 | ELISA WB | Biotin | Rabbit | IgG | AA 269-382 | Log in to see | Polyclonal | 0 | |
1 | ABIN2619144 | ELISA WB | Biotin | Rabbit | IgG | AA 476-592 | Log in to see | Polyclonal | 0 | |
1 | ABIN2619149 | ELISA WB | FITC | Rabbit | IgG | AA 269-382 | Log in to see | Polyclonal | 0 | |
1 | ABIN2619151 | ELISA WB | FITC | Rabbit | IgG | AA 34-159 | Log in to see | Polyclonal | 0 | |
1 | ABIN2619154 | ELISA WB | FITC | Rabbit | IgG | AA 476-592 | Log in to see | Polyclonal | 0 | |
1 | ABIN2619131 | ELISA WB | Rabbit | IgG | AA 34-159 | Log in to see | Polyclonal | 0 | ||
1 | ABIN2619138 | ELISA WB | Rabbit | IgG | AA 476-592 | Log in to see | Polyclonal | 0 |
General |
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Antigen | Complement Factor B (CFB) Antibodies |
Epitope | Internal Region Alternatives |
Reactivity | Human, Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This Complement Factor B antibody is un-conjugated Alternatives |
Application |
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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Supplier | Log in to see |
Product Details anti-Complement Factor B AntibodyTarget Details Complement Factor B Application Details Handling Images |
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Cross-Reactivity | Mouse (Murine), Rat (Rattus) |
Cross-Reactivity (Details) | Mouse (84 %), Rat (85 %) |
Characteristics |
Rabbit Polyclonal antibody to Factor B (complement factor B) Factor B antibody [N2C2], Internal |
Purification | Purified by antigen-affinity chromatography. |
Immunogen | Recombinant protein encompassing a sequence within the center region of human Factor B. The exact sequence is proprietary. |
Isotype | IgG |
Target Details Complement Factor BProduct Details anti-Complement Factor B Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | Factor B (CFB Antibody Abstract) |
Background |
This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. Cellular Localization: Secreted |
Molecular Weight | 86 kDa |
Gene ID | 629 |
Pathways | Complement System, Proton Transport, Ribonucleoside Biosynthetic Process |
Application DetailsProduct Details anti-Complement Factor B Antibody Target Details Complement Factor B Handling Images back to top |
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Application Notes | Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000* |
Comment |
Positive Control: Raji , K562 , Rat liver |
Restrictions | For Research Use only |
HandlingProduct Details anti-Complement Factor B Antibody Target Details Complement Factor B Application Details Images back to top |
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Format | Liquid |
Concentration | 0.87 mg/mL |
Buffer | 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative. |
Preservative | Thimerosal (Merthiolate) |
Precaution of Use | This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | -20 °C |
Storage Comment | Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
ImagesProduct Details anti-Complement Factor B Antibody Target Details Complement Factor B Application Details Handling back to top |
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Supplier Images |