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|Antigen||Kallikrein 9 (KLK9) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Kallikrein 9 antibody is conjugated to HRP Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-Kallikrein 9 AntibodyTarget Details Kallikrein 9 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human KLK9|
Target Details Kallikrein 9Product Details anti-Kallikrein 9 Antibody Application Details Handling Images back to top
|Alternative Name||Klk9 (KLK9 Antibody Abstract)|
Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in culture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The full length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain.
Synonyms: Kallikrein 8, Kallikrein 9, Kallikrein L3, Kallikrein Like 3, Kallikrein like protein 3, kallikrein related peptidase 9, Kallikrein-9, Kallikrein-like protein 3, Kallikrein8, Kallikrein9, KLK 8, KLK 9, KLK L3, KLK-L3, KLK8, KLK9, KLK9_HUMAN, KLKL 3, KLKL3.
Application DetailsProduct Details anti-Kallikrein 9 Antibody Target Details Kallikrein 9 Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-Kallikrein 9 Antibody Target Details Kallikrein 9 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.|
|Precaution of Use||This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|