anti-Dog (Canine) KLKB1 antibody for Western Blotting

Recommended KLKB1 Antibody (supplied by: Log in to see )

Antigen
Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) Antibodies
  • KLK3
  • PPK
  • APS
  • Kal-3
  • Kal3
  • Klk3
  • PSA
  • KALP15
  • Kalp1
  • KLKB1
  • DKFZp459J2015
  • klkb1
  • kallikrein B1
  • kallikrein B, plasma 1
  • plasma kallikrein
  • Plasma kallikrein
  • kallikrein B, plasma (Fletcher factor) 1
  • coagulation factor XI
  • kallikrein B1 L homeolog
  • KLKB1
  • Klkb1
  • CpipJ_CPIJ004042
  • CpipJ_CPIJ014955
  • CpipJ_CPIJ020108
  • VAA_02266
  • LOC100549617
  • klkb1
  • klkb1.L
Epitope
Middle Region
18
17
15
15
8
4
4
3
3
2
2
1
1
1
Reactivity
Dog (Canine), Horse (Equine), Human, Pig (Porcine), Rat (Rattus)
89
42
28
3
3
2
2
2
2
1
Host
Rabbit
84
22
6
3
1
Clonality
Polyclonal
Conjugate
This KLKB1 antibody is un-conjugated
8
8
8
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
75
66
23
17
14
14
13
2
2
2
2
1
1
Options
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Catalog No. ABIN2782312
$ 229.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4.8026066 ABIN2782313 WB Rabbit C-Term Log in to see Polyclonal 0
4 ABIN320970 WB Rabbit IgG AA 429-478 Log in to see Polyclonal 0
4 ABIN610831 WB Rabbit C-Term Log in to see Polyclonal 0

General

Antigen Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) Antibodies
Epitope Middle Region
(18), (17), (15), (15), (8), (4), (4), (3), (3), (2), (2), (1), (1), (1)
Reactivity Dog (Canine), Horse (Equine), Human, Pig (Porcine), Rat (Rattus)
(89), (42), (28), (3), (3), (2), (2), (2), (2), (1)
Host Rabbit
(84), (22), (6), (3), (1)
Clonality
Polyclonal
Conjugate This KLKB1 antibody is un-conjugated
(8), (8), (8), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(75), (66), (23), (17), (14), (14), (13), (2), (2), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-KLKB1 Antibody

Target Details KLKB1 Application Details Handling References for anti-KLKB1 antibody (ABIN2782312) Images
Sequence VLTAAHCFDG LPLQDVWRIY SGILNLSDIT KDTPFSQIKE IIIHQNYKVS
Predicted Reactivity Dog: 86%, Horse: 86%, Human: 100%, Pig: 79%, Rat: 79%
Characteristics This is a rabbit polyclonal antibody against KLKB1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human KLKB1
Plasmids, Primers & others

Target Details KLKB1

Product Details anti-KLKB1 Antibody Application Details Handling References for anti-KLKB1 antibody (ABIN2782312) Images back to top
Antigen
Alternative Name KLKB1 (KLKB1 Antibody Abstract)
Background Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
Alias Symbols: KLK3, PPK
Protein Interaction Partner: TFPI2, HGFAC, SERPINA5, F12, KNG1, IGFBP3, HGF, MST1,
Protein Size: 638
Molecular Weight 28 kDa
Gene ID 3818
NCBI Accession NM_000892, NP_000883
UniProt P03952
Pathways Complement System, Brown Fat Cell Differentiation

Application Details

Product Details anti-KLKB1 Antibody Target Details KLKB1 Handling References for anti-KLKB1 antibody (ABIN2782312) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 638 AA

Restrictions For Research Use only

Handling

Product Details anti-KLKB1 Antibody Target Details KLKB1 Application Details References for anti-KLKB1 antibody (ABIN2782312) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KLKB1 antibody (ABIN2782312)

Product Details anti-KLKB1 Antibody Target Details KLKB1 Application Details Handling Images back to top
Product cited in:

Tang, Yu, Williams, Springman, Jeffery, Sprengeler, Estevez, Sampang, Shrader, Spencer, Young, McGrath, Katz: "Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein." in: The Journal of biological chemistry, Vol. 280, Issue 49, pp. 41077-89, 2005

Images

Product Details anti-KLKB1 Antibody Target Details KLKB1 Application Details Handling References for anti-KLKB1 antibody (ABIN2782312) back to top
Supplier Images
Western Blotting (WB) image for anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (Middle Region) antibody (ABIN2782312) WB Suggested Anti-KLKB1 Antibody Titration: 2.5ug/ml Positive Control: Human Liver