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|Antigen||Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) Antibodies|
|Reactivity||Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This KLKB1 antibody is conjugated to Alexa Fluor 555 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-KLKB1 AntibodyTarget Details KLKB1 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic phosphopeptide derived from mouse APS around the phosphorylation site of Ser597|
|Plasmids, Primers & others|
Target Details KLKB1Product Details anti-KLKB1 Antibody Application Details Handling Images back to top
|Alternative Name||Aps (KLKB1 Antibody Abstract)|
APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family, an adaptor protein that is involved in B cell signaling, insulin signaling and cytoskeletal reorganisation. A PH and an SH2 domain containing adaptor protein that links activated tyrosine kinases to signaling pathways. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl.
Synonyms: Sh2b2, Aps, SH2B adapter protein 2, SH2 and PH domain-containing adapter protein APS, Adapter protein with pleckstrin homology and Src homology 2 domains, SH2B2_RAT.
|Pathways||Complement System, Brown Fat Cell Differentiation|
Application DetailsProduct Details anti-KLKB1 Antibody Target Details KLKB1 Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-KLKB1 Antibody Target Details KLKB1 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|