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SSH1A Antigen Profile
The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alternative names and synonyms associated with SSH1A
slingshot protein phosphatase 1 (SSH1) ELISA Kit
SSH1L ELISA Kit
Protein level used designations for SSH1A
SSH-like protein 1
, protein phosphatase Slingshot homolog 1
, slingshot homolog 1