anti-Mouse (Murine) ADCY1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ADCY1 Antibody

Antigen
Adenylate Cyclase 1 (Brain) (ADCY1) Antibodies
  • AC1
  • D11Bwg1392e
  • I-AC
  • brl
  • mKIAA4070
  • Ac1
  • adenylate cyclase 1
  • adenylate cyclase type 1
  • adenylate cyclase 1 (brain)
  • ADCY1
  • LOC100449504
  • adcy1
  • Adcy1
Reactivity
Human, Mouse (Murine)
71
47
28
4
3
Host
Rabbit
77
2
Clonality
Polyclonal
Conjugate
This ADCY1 antibody is un-conjugated
6
5
3
3
3
3
3
3
3
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
42
28
19
13
9
5
4
2
Options

Available images

Catalog No. ABIN498371
$ 434.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
7 ABIN2879425 ELISA IHC IHC (p) WB Rabbit IgG AA 231-280 Polyclonal 0
4 ABIN702565 IF (p) IHC (p) WB Rabbit IgG AA 795-845 Polyclonal 0
1 ABIN702574 IHC (p) WB HRP Rabbit IgG AA 795-845 Polyclonal 0
1 ABIN2879553 IHC IHC (p) WB Rabbit AA 230-280 Polyclonal 0
1 ABIN702567 IHC (p) WB Biotin Rabbit IgG AA 795-845 Polyclonal 0
1 ABIN2614551 IHC IHC (p) WB Rabbit Internal Region Polyclonal 0
1 ABIN2961717 IHC (p) ELISA WB Rabbit IgG AA 231-280 Polyclonal 0
1 ABIN2961718 IHC (p) WB Rabbit AA 230-280 Polyclonal 0

General

Antigen Adenylate Cyclase 1 (Brain) (ADCY1) Antibodies
Reactivity Human, Mouse (Murine)
(71), (47), (28), (4), (3)
Host Rabbit
(77), (2)
Clonality
Polyclonal
Conjugate This ADCY1 antibody is un-conjugated
(6), (5), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(42), (28), (19), (13), (9), (5), (4), (2)
Supplier

Product Details anti-ADCY1 Antibody

Target Details ADCY1 Application Details Handling Images
Specificity This antibody detects endogenous levels of A Cyclase I protein. (region surrounding Asp252)
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE
Plasmids, Primers & others

Target Details ADCY1

Product Details anti-ADCY1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Adenylate Cyclase Type 1 (ADCY1 Antibody Abstract)
Background Adenylyl cyclases function to convert ATP to cyclic AMP in response to activation by a variety of hormones, neurotransmitters and other regulatory molecules. Cyclic AMP, in turn, activates several other target molecules to control a broad range of diverse phenomena such as metabolism, gene transcription and memory. Adenylyl cyclases respond to receptor-initiated signals, mediated by the Gs and Gi heterotrimeric G proteins. The binding of an agonist to a Gs-coupled receptor catalyzes the exchange of GDP (bound to Galpha s) for GTP, the dissociation of GTP-Galpha s from Gbeta-gamma and Galpha s)-mediated activation of adenylyl cyclase. Adenylyl cyclases type I (AC I) and III (AC III) have distinct staining within the cell nucleus of rat brain sensory neurons. AC I is expressed in myenteric ganglia as two bands of 160 kDa and 185 kDa by SDS-PAGE. Ca2+ stimulation of AC I and AC III is mediated by calmodulin. Protein associated with Myc (PAM) is a very potent inhibitor of AC I. A decrease in endogenous PAM levels in HeLa cells modulate both basal and agonist stimulated cAMP accumulation.Synonyms: ADCY1, ATP pyrophosphate-lyase 1, Adenylate cyclase type I, Adenylyl cyclase 1, Ca(2+)/calmodulin-activated adenylyl cyclase
Molecular Weight approx. 130 kDa
Gene ID 107
NCBI Accession NP_066939
UniProt Q08828
Pathways EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma

Application Details

Product Details anti-ADCY1 Antibody Target Details ADCY1 Handling Images back to top
Application Notes Western Blot: 1/500- 1/1000. Immuohistochemistry: 1/50- 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-ADCY1 Antibody Target Details ADCY1 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-ADCY1 Antibody Target Details ADCY1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Adenylate Cyclase 1 (Brain) (ADCY1) antibody (ABIN498371) Immunohistochemistry (IHC) analyzes of A Cyclase I antibosy in paraffin-embedded huma...
Western Blotting (WB) image for anti-Adenylate Cyclase 1 (Brain) (ADCY1) antibody (ABIN498371) Western blot (WB) analysis of A Cyclase I antibody in extracts from COLO205 cells.