anti-Human Adenylate Cyclase 7 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Adenylate Cyclase 7 Antibody (supplied by: Log in to see )

Antigen
Adenylate Cyclase 7 (Adcy7) Antibodies
  • ADCY7
  • ADCY4a
  • AC7
  • AA407758
  • ac7
  • adenylate cyclase 7
  • adenylate cyclase 7 L homeolog
  • ADCY7
  • adcy7
  • Adcy7
  • adcy7.L
Epitope
AA 510-539, Center
15
3
3
2
2
2
1
1
Reactivity
Human
35
26
19
Host
Rabbit
36
1
Clonality
Polyclonal
Conjugate
Un-conjugated
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
17
14
13
12
7
7
5
3
3
2
2
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Catalog No. ABIN653337
$ 385.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7 ABIN751213 IF (p) IHC (p) WB Rabbit IgG AA 905-955 Log in to see Polyclonal 0
7 ABIN5572037 ELISA IF IHC IHC (p) Rabbit Log in to see Polyclonal 0
1 ABIN751222 IHC (p) WB HRP Rabbit IgG AA 905-955 Log in to see Polyclonal 0
1 ABIN751215 IHC (p) WB Biotin Rabbit IgG AA 905-955 Log in to see Polyclonal 0
1 ABIN2883442 ELISA IF IHC IHC (p) Rabbit IgG AA 191-240 Log in to see Polyclonal 0
1 ABIN1805693 FACS IHC IHC (p) WB Rabbit AA 510-539 Log in to see Polyclonal 0
-3.527007 ABIN4278419 IHC IHC (p) Rabbit IgG Log in to see Polyclonal 0

General

Antigen Adenylate Cyclase 7 (Adcy7) Antibodies
Epitope AA 510-539, Center
(15), (3), (3), (2), (2), (2), (1), (1)
Reactivity Human
(35), (26), (19)
Host Rabbit
(36), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate Un-conjugated
(2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(17), (14), (13), (12), (7), (7), (5), (3), (3), (2), (2)
Pubmed 3 references available
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Product details

Target Details Application Details Handling References Images
Specificity This ADCY7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 517~547 amino acids from the Center region of human ADCY7.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This ADCY7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 510-539 AA from the Central region of human ADCY7.
Clone RB22830
Isotype Ig Fraction

Target Details

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Antigen
Alternative Name ADCY7 (Adcy7 Antibody Abstract)
Background ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences.
Synonyms: Adenylyl cyclase 7, ATP pyrophosphate-lyase 7, Adenylate cyclase type VII, Adenylate cyclase type 7, KIAA0037, ADCY7
Molecular Weight 120308 DA
Gene ID 113
UniProt P51828
Pathways EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma

Application Details

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Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References

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Background publications

Townsend, Holliday, Fenyk, Hess, Gray, Hodgson, Cann: "Stimulation of mammalian G-protein-responsive adenylyl cyclases by carbon dioxide." in: The Journal of biological chemistry, Vol. 284, Issue 2, pp. 784-91, 2009

Jiang, Collins, Davis, Fraser, Sternweis: "Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23429-39, 2008

Hines, Hoffman, Bhave, Saba, Kaiser, Snell, Goncharov, LeGault, Dongier, Grant, Pronko, Martinez, Yoshimura, Tabakoff,: "A sex-specific role of type VII adenylyl cyclase in depression." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 48, pp. 12609-19, 2006

Images

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Supplier Images
Western Blotting (WB) image for anti-Adenylate Cyclase 7 (Adcy7) (AA 510-539), (Center) antibody (ABIN653337) Western blot analysis of ADCY7 Antibody (Center) (ABIN653337) in MCF-7 cell line lysa...
Immunohistochemistry (IHC) image for anti-Adenylate Cyclase 7 (Adcy7) (AA 510-539), (Center) antibody (ABIN653337) Formalin-fixed and paraffin-embedded human breast carcinoma reacted with ADCY7 Antibo...
Flow Cytometry (FACS) image for anti-Adenylate Cyclase 7 (Adcy7) (AA 510-539), (Center) antibody (ABIN653337) ADCY7 Antibody (Center) (ABIN653337) flow cytometric analysis of MCF-7 cells (bottom ...