EPOR Products
(Erythropoietin Receptor (EPOR))
Categories
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
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Featured EPOR Categories
EPOR Antibodies
High quality antibodies with extensive validation data.
EPOR ELISA Kits
Reliable ELISA kits for a wide range of species.
EPOR Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EPOR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (6)
Cat. No.
ABIN560776
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
- (4)
Cat. No.
ABIN686347
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (5)
Cat. No.
ABIN6243002
Quantity
400 μL
Datasheet
Datasheet
Recommended EPOR ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6955646
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955647
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1979359
Quantity
96 tests
Datasheet
Datasheet
Recommended EPOR Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122817
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352979
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352977
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our EPOR products
: "High-Altitude Hypoxia Decreases Plasma Erythropoietin Soluble Receptor Concentration in Lowlanders." in: High altitude medicine & biology, Vol. 21, Issue 1, pp. 92-98, (2020) (PubMed).: "Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice." in: Redox biology, Vol. 24, pp. 101192, (2019) (PubMed).
: "The Effects of Curcumae Longae Radix, Curcuma phaeocaulis Radix and Their Processed Products on Epo/EpoR Pathway and CD62p." in: Frontiers in pharmacology, Vol. 9, pp. 736, (2018) (PubMed).
: "Plasma soluble erythropoietin receptor is decreased during sleep in Andean highlanders with Chronic Mountain Sickness." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 121, Issue 1, pp. 53-8, (2016) (PubMed).
: "Oxidative stress induces the decline of brain EPO expression in aging rats." in: Experimental gerontology, Vol. 83, pp. 89-93, (2016) (PubMed).
: "Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations." in: Molecular medicine reports, Vol. 15, Issue 1, pp. 228-234, (2016) (PubMed).
: "Pretreatment With Erythropoietin Attenuates Intestinal Ischemia Reperfusion Injury by Further Promoting PI3K/Akt Signaling Activation." in: Transplantation proceedings, Vol. 47, Issue 6, pp. 1639-45, (2016) (PubMed).
: "Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. ..." in: British journal of haematology, Vol. 168, Issue 3, pp. 429-42, (2015) (PubMed).
: "Engineering of erythropoietin receptor for use as an affinity ligand." in: Protein expression and purification, Vol. 111, pp. 1-8, (2015) (PubMed).
: "Decreased plasma soluble erythropoietin receptor in high-altitude excessive erythrocytosis and Chronic Mountain Sickness." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 117, Issue 11, pp. 1356-62, (2014) (PubMed).
Synonyms and alternative names related to EPOR
erythropoietin receptor (EPOR), erythropoietin receptor (epor), erythropoietin receptor (Epor), erythropoietin receptor L homeolog (epor.L), EPO-R, EPOR, eporProtein level used designations for EPOR
- erythropoietin receptor
- Erythropoietin receptor
- type I single-transmembrane cytokine receptor
- erythropoietin receptor-like
- EPO-R
- xlEPOR
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