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Mouse (Murine) Polyclonal CASP12 Primary Antibody for IF (p), IHC (p) - ABIN737736
Zhang, Lv, Zhao, Jia, Zhang, Xiao, Wang, Li, Ji, Tian, Li, Fan, Lai, Liu, Li, Zhang, Liu, Guo, Han, Ji: Glucose-regulated protein 78 may play a crucial role in promoting the pulmonary microvascular remodeling in a rat model of hepatopulmonary syndrome. in Gene 2014
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Mouse (Murine) Polyclonal CASP12 Primary Antibody for WB - ABIN223032
Chin, Lin, Kuo, Chueh: Dual effect of thapsigargin on cell death in porcine aortic smooth muscle cells. in American journal of physiology. Cell physiology 2007
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Human Polyclonal CASP12 Primary Antibody for - ABIN550325
Van de Craen, Vandenabeele, Declercq, Van den Brande, Van Loo, Molemans, Schotte, Van Criekinge, Beyaert, Fiers: Characterization of seven murine caspase family members. in FEBS letters 1997
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Human Polyclonal CASP12 Primary Antibody for WB - ABIN967345
Nakagawa, Zhu, Morishima, Li, Xu, Yankner, Yuan: Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. in Nature 2000
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Human Polyclonal CASP12 Primary Antibody for ELISA, WB - ABIN4288058
Lee, Lee, Park, Sharoar, Shin, Lee, Cho, Park: Purification of catalytically active caspase-12 and its biochemical characterization. in Archives of biochemistry and biophysics 2010
Human Polyclonal CASP12 Primary Antibody for ELISA, ICC - ABIN4288054
Nakagawa, Yuan: Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. in The Journal of cell biology 2000
mice ablated for caspase-12 develop spontaneous obesity and insulin (show INS Antibodies) resistance.
Bnip3L (show BNIP3L Antibodies) and caspase-12 identified by the PCR arrays at both catagen stages were additionally localized using immunofluorescence and were reported in physiological hair development for the first time.
Caspase-12 plays a pivotal role in CCl4 (show CCL4 Antibodies)-induced hepatic apoptosis through the activation of the downstream effector caspase-3 (show CASP3 Antibodies) directly and/or indirectly via caspase-9 (show CASP9 Antibodies) activation.
We validated caspase-12 as a therapeutic target, ablation of which significantly protects T17M photoreceptors from deterioration.
Findings an increase in multiple unfolded protein response pathways in muscles of the dystrophin (show DMD Antibodies)-deficient mdx (show DMD Antibodies) mouse, the model for Duchenne muscular dystrophy (show DMD Antibodies).
Tauroursodeoxycholic acid intervention down-regulated GRP78 (show HSPA5 Antibodies) and CHOP (show DDIT3 Antibodies) expression and Caspase 12 activation.
Findings indicate that although caspase-12 deficiency results in enhanced pro-inflammatory and immunoregulatory cytokine levels in sera during P. yoelii 17XL infection, these responses are not essential for protection against lethal malaria infection.
caspase-12 competed with NEMO (show IKBKG Antibodies) for association with IkappaB kinase-alpha (show CHUK Antibodies)/beta, effectively preventing the formation of the IkappaB kinase (show CHUK Antibodies) complex and inhibiting downstream transcriptional activation by NF-kappaB (show NFKB1 Antibodies).
Caspase-12 was required for an effective antiviral immune response, especially for the production of type I interferons through the regulation of TRIM25 (show TRIM25 Antibodies)-mediated ubiquitination of RIG-I (show DDX58 Antibodies). .
Matrix metalloproteinase-3 (show MMP3 Antibodies) is increased and participates in neuronal apoptotic signaling downstream of caspase-12 during endoplasmic reticulum stress
cysteine-aspartic acid protease (caspase); involved with the terminal stage of apoptosis