anti-Rat (Rattus) Caspase 12 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended Caspase 12 Antibody (supplied by: Log in to see )

Antigen
Caspase 12 (CASP12) Antibodies
  • Caspase-12
  • caspase 12
  • Casp12
  • CASP12
Epitope
AA 240-290
14
14
13
12
12
10
9
7
5
5
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
101
99
69
Host
Rabbit
128
14
12
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
140
62
60
38
18
16
15
12
10
6
3
1
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Catalog No. ABIN737736
$ 318.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN886672 IF (p) Alexa Fluor 488 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN737739 IF (p) Cy3 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN737740 IF (p) Cy5 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN737741 IF (p) Cy5.5 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN737742 IF (p) Cy7 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN737743 IF (p) FITC Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN886676 IF (p) Alexa Fluor 647 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN886675 IF (p) Alexa Fluor 350 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN886674 IF (p) Alexa Fluor 555 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN2811125 IF (p) Alexa Fluor 594 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN4999076 IF (p) Alexa Fluor 680 Rabbit IgG AA 240-290 Log in to see Polyclonal 0
1 ABIN4999077 IF (p) Alexa Fluor 750 Rabbit IgG AA 240-290 Log in to see Polyclonal 0

General

Antigen Caspase 12 (CASP12) Antibodies
Epitope AA 240-290
(14), (14), (13), (12), (12), (10), (9), (7), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine), Rat (Rattus)
(101), (99), (69)
Host Rabbit
(128), (14), (12)
Clonality
Polyclonal
Conjugate Un-conjugated
(4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(140), (62), (60), (38), (18), (16), (15), (12), (10), (6), (3), (1)
Pubmed 6 references available
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Product details

Target Details Application Details Handling References Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse Caspase 12
Isotype IgG

Target Details

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Antigen
Alternative Name Caspase 12 (CASP12 Antibody Abstract)
Background

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011].

Subcellular location: Cytoplasm

Synonyms: Caspase-12, CASP-12, Casp12

Gene ID 12364
UniProt O08736
Pathways ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

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Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References

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Product cited in:

Wang, Xuan, Cui, Wang, Chen, Wei, Zhao: "Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes." in: PLoS ONE, Vol. 12, Issue 4, pp. e0173469, 2017 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Rat (Rattus)).

Yu, Zhang, Zhao, Guo, Li, Li, Zhang, Sun: "Gypenoside Protects against Myocardial Ischemia-Reperfusion Injury by Inhibiting Cardiomyocytes Apoptosis via Inhibition of CHOP Pathway and Activation of PI3K/Akt Pathway In Vivo and In Vitro." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 1, pp. 123-36, 2016 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: myocardial tissues

Wang, Wang, Huang, Yang, Zhao, Wei, Zhao: "Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways." in: Heart and vessels, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: myocardium of cardiomyopathy

Zhou, Zhou, Yu, Wu, Chen, Zhao et al.: "Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ..." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 43-52, 2015 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Rat (Rattus)).

Zhang, Zhang, Lv, Jia, Fan, Tian, Li, Li, Ji, Wang, Zhao, Han, Ji: "Increased expression of 78 kD glucose-regulated protein promotes cardiomyocyte apoptosis in a rat model of liver cirrhosis." in: International journal of clinical and experimental pathology, Vol. 8, Issue 8, pp. 9256-63, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)). Further details: Sample: Liver

Zhang, Lv, Zhao, Jia, Zhang, Xiao, Wang, Li, Ji, Tian, Li, Fan, Lai, Liu, Li, Zhang, Liu, Guo, Han, Ji: "Glucose-regulated protein 78 may play a crucial role in promoting the pulmonary microvascular remodeling in a rat model of hepatopulmonary syndrome." in: Gene, Vol. 545, Issue 1, pp. 156-62, 2014 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)). Further details: Sample: Lung

Images

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Supplier Images
Immunohistochemistry (IHC) image for anti-Caspase 12 (CASP12) (AA 240-290) antibody (ABIN737736) Formalin-fixed and paraffin embedded rat testis tissue (high fat) labeled with Anti-N...
ELISA image for anti-Caspase 12 (CASP12) (AA 240-290) antibody (ABIN737736) Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 12 (CASP12) (AA 240-290) antibody (ABIN737736) Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti-Caspase 12 P...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 12 (CASP12) (AA 240-290) antibody (ABIN737736) Formalin-fixed and paraffin embedded rat testis tissue (high fat) labeled with Anti-N...
Western Blotting (WB) image for anti-Caspase 12 (CASP12) (AA 240-290) antibody (ABIN737736) Lane 1: Mouse Cerebrum lysates Lane 2: Rat Cerebrum lysates probed with Caspase 12 Po...