anti-Rat (Rattus) CTH antibody for Western Blotting

Recommended CTH Antibody (supplied by: Log in to see )

Antigen
Cystathionase (Cystathionine gamma-Lyase) (CTH) Antibodies
  • CTH
  • cysA
  • SCQ11.03c
  • DDBDRAFT_0190313
  • DDBDRAFT_0191318
  • DDB_0190313
  • DDB_0191318
  • MGC75946
  • wu:fb48e03
  • wu:fb58d08
  • zgc:66001
  • zgc:85785
  • 0610010I13Rik
  • AI314617
  • BC019483
  • CSE
  • Cys3
  • H
  • cystathionine gamma-lyase
  • cystathionine gamma-lyase L homeolog
  • cystathionase (cystathionine gamma-lyase)
  • CTH
  • SCO3920
  • mlr1566
  • TA_RS00415
  • MAP_RS15640
  • SPO3344
  • CNN01730
  • Mmcs_1928
  • RHA1_RS31820
  • HNE_1212
  • MAV_3867
  • MSMEG_2394
  • Mvan_2142
  • SACE_6136
  • Mflv_4220
  • cysA
  • cth
  • cth.L
  • Cth
Epitope
AA 112-131, Middle Region
17
6
5
5
4
2
2
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
77
43
38
6
6
3
3
3
2
2
2
1
Host
Rabbit
66
21
Clonality
Polyclonal
Conjugate
This CTH antibody is un-conjugated
4
4
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
71
28
19
15
13
10
6
5
2
1
1
Options
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Catalog No. ABIN3044240
$ 240.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.342568 ABIN3042672 IHC (p) WB Rabbit IgG AA 316-331, C-Term Log in to see Polyclonal 5
12.342568 ABIN3042770 WB Rabbit IgG AA 181-398 Log in to see Polyclonal 5
12.342568 ABIN2782463 WB Rabbit N-Term Log in to see Polyclonal 4
12.342568 ABIN2782464 IHC WB Rabbit C-Term Log in to see Polyclonal 2
12.342568 ABIN1387469 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
10.842568 ABIN3030651 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
7.842569 ABIN1862361 ICC IHC WB Rabbit IgG AA 36-299 Log in to see Polyclonal 0
7.842569 ABIN2897936 IF/ICC IHC IP WB Rabbit AA 36-299 Log in to see Polyclonal 0
7.7166495 ABIN441751 IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal 0
4.842569 ABIN2704684 WB Rabbit C-Term Log in to see Polyclonal 0
4.842569 ABIN1877107 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2619625 IHC IHC (p) WB Rabbit IgG AA 316-331 Log in to see Polyclonal 0
1 ABIN1805435 ELISA WB Mouse IgG1, kappa AA 1-405 Log in to see 4E1-1B7 0
1 ABIN6759538 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2597153 WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN1421044 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal 0
1 ABIN2887485 IHC WB Rabbit Log in to see Polyclonal 0
1 ABIN6710620 WB Rabbit Log in to see Polyclonal 0
1 ABIN1403173 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN6091490 ELISA IF/ICC IHC WB Rabbit IgG AA 1-70 Log in to see Polyclonal 0

General

Antigen Cystathionase (Cystathionine gamma-Lyase) (CTH) Antibodies
Epitope AA 112-131, Middle Region
(17), (6), (5), (5), (4), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(77), (43), (38), (6), (6), (3), (3), (3), (2), (2), (2), (1)
Host Rabbit
(66), (21)
Clonality
Polyclonal
Conjugate This CTH antibody is un-conjugated
(4), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(71), (28), (19), (15), (13), (10), (6), (5), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-CTH Antibody

Target Details CTH Application Details Handling References for anti-CTH antibody (ABIN3044240) Images
Purpose Rabbit IgG polyclonal antibody for Cystathionine gamma-lyase(CTH) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Sequence DVYGGTNRYF RQVASEFGLK
Cross-Reactivity (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Characteristics Rabbit IgG polyclonal antibody for Cystathionine gamma-lyase(CTH) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: cystathionase(cystathionine gamma-lyase)
Protein Name: Cystathionine gamma-lyase
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human Cystathionase(112-131aa DVYGGTNRYFRQVASEFGLK), different from the related rat and mouse sequences by two amino acids.
Isotype IgG
Plasmids, Primers & others

Target Details CTH

Product Details anti-CTH Antibody Application Details Handling References for anti-CTH antibody (ABIN3044240) Images back to top
Antigen
Alternative Name CTH (CTH Antibody Abstract)
Background CTH(CYSTATHIONINE GAMMA-LYASE),also called CYSTATHIONASE, is an enzyme which breaks down cystathionine into cysteine and alpha-ketobutyrate.And the CTH gene is mapped on 1p31.1. In some bacteria and mammals, including humans, this enzyme takes part in generating hydrogen sulfide and that genetic deletion of this enzyme in mice markedly reduced H2S levels in the serum, heart, aorta, and other tissues. Mutant mice lacking CTH displayed pronounced hypertension and diminished endothelium-dependent vasorelaxation. Cystathionine was physiologically activated by calcium and calmodulin, which is a mechanism for H2S formation in response to vascular activation.

Synonyms: CGL_HUMAN antibody|CTH antibody|cystathionase(cystathionine gamma-lyase) antibody|Cystathionine gamma lyase antibody|Cystathionine gamma-lyase antibody|Cysteine desulfhydrase antibody|Gamma cystathionase antibody|Gamma-cystathionase antibody|Homoserine deaminase antibody|Homoserine dehydratase antibody|MGC9471 antibody
UniProt P32929
Pathways ER-Nucleus Signaling

Application Details

Product Details anti-CTH Antibody Target Details CTH Handling References for anti-CTH antibody (ABIN3044240) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions For Research Use only

Handling

Product Details anti-CTH Antibody Target Details CTH Application Details References for anti-CTH antibody (ABIN3044240) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Expiry Date 12 months

References for anti-CTH antibody (ABIN3044240)

Product Details anti-CTH Antibody Target Details CTH Application Details Handling Images back to top
Product cited in:

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, 2018

Qi, Zhao, Li, Shao, Wang, Sui, Yu, Shao, Gui, Li, Jia, Jiang, Li, Zhang, Wang, Wang: "High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways." in: International journal of oncology, Vol. 53, Issue 1, pp. 358-370, 2018

Shi, Guo, Shi, Yu, Song, Li: "Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 2774-80, 2016

Chen, Wang, Li, Jiang, Lu, Zhou: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 9726503, 2016

Guo, Duan, Wang, Zhou, Li, Sun: "Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis." in: Experimental and therapeutic medicine, Vol. 10, Issue 6, pp. 2039-2046, 2015

Images

Product Details anti-CTH Antibody Target Details CTH Application Details Handling References for anti-CTH antibody (ABIN3044240) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 112-131), (Middle Region) antibody (ABIN3044240) Anti-Cystathionase antibody, IHC(P) IHC(P): Rat Liver Tissue
Western Blotting (WB) image for anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 112-131), (Middle Region) antibody (ABIN3044240) Anti-Cystathionase antibody,Western blotting All lanes: Anti Cystathionase at 0.5ug/...
Immunohistochemistry (IHC) image for anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 112-131), (Middle Region) antibody (ABIN3044240) Anti-Cystathionase antibody, ICC ICC: SMMC Cell