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|Antigen||Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies|
|Epitope||AA 563-579 Alternatives|
|Reactivity||Cow (Bovine), Dog (Canine), Guinea Pig, Hamster, Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine), Xenopus laevis Alternatives|
|Conjugate||This MAP3K7 antibody is un-conjugated Alternatives|
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-MAP3K7 AntibodyTarget Details MAP3K7 Application Details Handling Images
|Specificity||Detects an ~70 kD protein, corresponding to the apparent molecular mass of TAK1 on SDS-PAGE immunoblots.|
|Purification||Protein A purified|
Synthetic peptide based on mouse TAK1 (residues 563-579) (1) with a cysteine C residue added and the peptide coupled to KLH.
Type of Immunogen: Synthetic peptide - KLH conjugated
Target Details MAP3K7Product Details anti-MAP3K7 Antibody Application Details Handling Images back to top
|Alternative Name||MAP3K7 / TAK1 (MAP3K7 Antibody Abstract)|
Name/Gene ID: MAP3K7
Family: Protein Kinase
Synonyms: MAP3K7, MEKK7, TGF-beta activated kinase 1, TGF1a, TAK1, TGF-beta-activated kinase 1
|Pathways||NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades|
Application DetailsProduct Details anti-MAP3K7 Antibody Target Details MAP3K7 Handling Images back to top
Approved: IHC, IHC-P (5 - 10 μg/mL), WB
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.
Target Species of Antibody: Mouse
|Restrictions||For Research Use only|
HandlingProduct Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details Images back to top
|Buffer||PBS, pH 7.2, 0.09 % sodium azide, 50 % glycerol.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeat freeze-thaw cycles.|
Short term: -20°C
Long term: -20°C.
ImagesProduct Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details Handling back to top