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Four and A Half LIM Domains 2 Products

(Four and A Half LIM Domains 2 (FHL2))

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This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011].

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Featured Four and A Half LIM Domains 2 Categories

Four and A Half LIM Domains 2 Antibodies

High quality antibodies with extensive validation data.

Four and A Half LIM Domains 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Four and A Half LIM Domains 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Four and A Half LIM Domains 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (4)
Cat. No. ABIN515657
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7237012
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN560901
Quantity 100 μg
Datasheet Datasheet

Recommended Four and A Half LIM Domains 2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5592045
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6204329
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN2870037
Quantity 96 tests
Datasheet Datasheet

Recommended Four and A Half LIM Domains 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354076
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3080102
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131998
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Four and A Half LIM Domains 2 products

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Li, Ponten, dos Remedios: "The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development." in: Proteomics, Vol. 12, Issue 2, pp. 203-25, (2012) (PubMed).

Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).

Han, Wu, Zhao, Meng, Si, Yang, Fu, Yu: "FHL2 interacts with and acts as a functional repressor of Id2 in human neuroblastoma cells." in: Nucleic acids research, Vol. 37, Issue 12, pp. 3996-4009, (2009) (PubMed).

Saeki, Endo, Ide, Nagashima, Yumoto, Toyoda, Suzuki, Hayashizaki, Sakaki, Okada-Hatakeyama: "Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells." in: BMC genomics, Vol. 10, pp. 545, (2009) (PubMed).

Pontén, Gry, Fagerberg, Lundberg, Asplund, Berglund, Oksvold, Björling, Hober, Kampf, Navani, Nilsson, Ottosson, Persson, Wernérus, Wester, Uhlén: "A global view of protein expression in human cells, tissues, and organs." in: Molecular systems biology, Vol. 5, pp. 337, (2009) (PubMed).

Kudo, Karsten, Chen, Levitt, Geschwind: "Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 17, Issue 9, pp. 2108-22, (2007) (PubMed).

Nair, Guo, Mueller, Koochekpour, Qiu, Tekmal, Schüle, Kung, Kumar, Vadlamudi et al.: "Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only ..." in: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 3, pp. 613-24, (2007) (PubMed).

Lee, Chung, Kang: "Combined treatment of high pressure and heat on killing spores of Alicyclobacillus acidoterrestris in apple juice concentrate." in: Journal of food protection, Vol. 69, Issue 5, pp. 1056-60, (2006) (PubMed).

Kahl, Gullotti, Heukamp, Wolf, Friedrichs, Vorreuther, Solleder, Bastian, Ellinger, Metzger, Schüle, Buettner: "Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence." in: Cancer research, Vol. 66, Issue 23, pp. 11341-7, (2006) (PubMed).

Synonyms and alternative names related to Four and A Half LIM Domains 2

four and a half LIM domains 2 (FHL2), four and a half LIM domains 2 (Fhl2), four and a half LIM domains 2 (fhl2), four and a half LIM domains 2a (fhl2a), four and a half LIM domains 2b (fhl2b), AAG11, C76204, DRAL, FHL-2, FHL2, SLIM-3, SLIM3, zgc:92428, zgc:103466

Protein level used designations for Four and A Half LIM Domains 2

  • LIM domain protein DRAL
  • aging-associated gene 11
  • down-regulated in rhabdomyosarcoma LIM protein
  • four and a half LIM domains protein 2
  • skeletal muscle LIM-protein 3
  • FHL-2
  • SLIM-3
  • SLIM 3
  • four and a half LIM domains 2
  • DKEYP-118H3.4
  • four and half LIM domains protein 2
  • four and a half LIM domains 2b
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