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Rap Guanine Nucleotide Exchange Factor (GEF) 1 Products

(Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

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This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].

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Featured Rap Guanine Nucleotide Exchange Factor (GEF) 1 Categories

Rap Guanine Nucleotide Exchange Factor (GEF) 1 Antibodies

High quality antibodies with extensive validation data.

Rap Guanine Nucleotide Exchange Factor (GEF) 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Rap Guanine Nucleotide Exchange Factor (GEF) 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Rap Guanine Nucleotide Exchange Factor (GEF) 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN561125
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7269849
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN6243613
Quantity 400 μL
Datasheet Datasheet

Recommended Rap Guanine Nucleotide Exchange Factor (GEF) 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN511558
Quantity 96 tests
Datasheet Datasheet
Reactivity Goat
Analytical Method
Validations
Cat. No. ABIN995293
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative
Validations
Cat. No. ABIN995294
Quantity 96 tests
Datasheet Datasheet

Recommended Rap Guanine Nucleotide Exchange Factor (GEF) 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317408
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3095122
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416172
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Rap Guanine Nucleotide Exchange Factor (GEF) 1 products

Nolz, Nacusi, Segovis, Medeiros, Mitchell, Shimizu, Billadeau: "The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1." in: The Journal of cell biology, Vol. 182, Issue 6, pp. 1231-44, (2008) (PubMed).

Lachmann, Pangburn, Oldroyd: "Breakdown of C3 after complement activation. Identification of a new fragment C3g, using monoclonal antibodies." in: The Journal of experimental medicine, Vol. 156, Issue 1, pp. 205-16, (1982) (PubMed).

Lachmann, Oldroyd, Milstein, Wright: "Three rat monoclonal antibodies to human C3." in: Immunology, Vol. 41, Issue 3, pp. 503-15, (1981) (PubMed).

Synonyms and alternative names related to Rap Guanine Nucleotide Exchange Factor (GEF) 1

Rap guanine nucleotide exchange factor 1 (RAPGEF1), Rap guanine nucleotide exchange factor like 1 (RAPGEFL1), Rap guanine nucleotide exchange factor (GEF) 1 (Rapgef1), Rap guanine nucleotide exchange factor 1 S homeolog (rapgef1.S), Rap guanine nucleotide exchange factor 1 (rapgef1), Rap guanine nucleotide exchange factor (GEF) 1 (RAPGEF1), Rap guanine nucleotide exchange factor 1 (Rapgef1), Rap guanine nucleotide exchange factor (GEF) 1b (rapgef1b), Rap guanine nucleotide exchange factor like 1 (Rapgefl1), 4932418O06Rik, C3G, C3g, C3G-1, C3G-2, GRF2, Grf2, Link-GEFII, RAPGEF1, rapgef1, zgc:56372

Protein level used designations for Rap Guanine Nucleotide Exchange Factor (GEF) 1

  • CRK SH3-binding GNRP
  • guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)
  • rap guanine nucleotide exchange factor 1
  • Link guanine nucleotide exchange factor II
  • RAP guanine-nucleotide-exchange factor (GEF)-like 1
  • link GEFII
  • rap guanine nucleotide exchange factor-like 1
  • guanine nucleotide releasing factor 2
  • guanine nucleotide-releasing factor 2
  • Rap guanine nucleotide exchange factor (GEF) 1
  • rap guanine nucleotide exchange factor 1-like
  • Rap guanine nucleotide exchange factor (GEF)-like 1
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