anti-Human BMPR2 antibody for Immunofluorescence

Recommended BMPR2 Antibody (supplied by: Log in to see )

Antigen
Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) Antibodies
  • BMPR-II
  • BMPR3
  • BMR2
  • BRK-3
  • PPH1
  • T-ALK
  • 2610024H22Rik
  • AL117858
  • AW546137
  • BB189135
  • BMP-2
  • BMPR-2
  • BMPRII
  • Gm20272
  • Bmpr-II
  • bmprii
  • bone morphogenetic protein receptor type 2
  • bone morphogenetic protein receptor, type II b (serine/threonine kinase)
  • bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • BMPR2
  • bmpr2b
  • Bmpr2
Reactivity
Human, Mouse (Murine), Rat (Rattus), Monkey
155
77
54
13
3
2
Host
Mouse
102
47
7
Clonality
Monoclonal
Conjugate
This BMPR2 antibody is un-conjugated
7
6
5
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
117
80
78
36
31
22
13
13
5
3
3
1
Options
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Catalog No. ABIN965687
$ 577.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
17.512884 ABIN5573317 ELISA IF IHC (p) WB Mouse IgG1 Log in to see 3F6 0
17.512884 ABIN1105549 EIA IF IHC (p) WB Mouse IgG1 Log in to see 3F6 2
13.252602 ABIN4901095 ELISA IF IHC (p) WB Mouse IgG1 Log in to see 3F6 0
13.252602 ABIN5622992 ELISA IF IHC WB Mouse IgG Log in to see M81935 0
13.252602 ABIN2134832 IF IHC ELISA WB Mouse IgG1 Log in to see M81252 0
5.4926057 ABIN5683096 ELISA ICC IF IHC WB Mouse IgG1 Log in to see 3F6 0
4 ABIN1959872 ELISA IF IHC IHC (p) WB Mouse IgG1 Log in to see 3F6 0
1 ABIN1966228 ELISA FACS ICC IF IHC WB Biotin Rabbit IgG AA 28-59 Log in to see Polyclonal 0
1 ABIN1970030 ELISA FACS ICC IF IHC WB FITC Rabbit IgG AA 28-59 Log in to see Polyclonal 0
1 ABIN1963585 ELISA FACS ICC IF IHC WB APC Rabbit IgG AA 28-59 Log in to see Polyclonal 0
1 ABIN1973306 ELISA FACS ICC IF IHC WB HRP Rabbit IgG AA 28-59 Log in to see Polyclonal 0
1 ABIN1961208 ELISA FACS ICC IF IHC WB Alkaline Phosphatase (AP) Rabbit IgG AA 28-59 Log in to see Polyclonal 0
1 ABIN2617707 ELISA FACS IF IHC WB Rabbit IgG AA 28-59 Log in to see Polyclonal 0
1 ABIN1974616 ELISA FACS ICC IF IHC WB PE Rabbit IgG AA 28-59 Log in to see Polyclonal 0
1 ABIN2211350 FACS IF IHC ELISA WB APC Rabbit IgG AA 28-59, N-Term Log in to see Polyclonal 0
1 ABIN2211352 FACS IF IHC ELISA WB FITC Rabbit IgG AA 28-59, N-Term Log in to see Polyclonal 0
1 ABIN2211354 FACS IF IHC ELISA WB PE Rabbit IgG AA 28-59, N-Term Log in to see Polyclonal 0
1 ABIN2211349 FACS IF IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 28-59, N-Term Log in to see Polyclonal 0
1 ABIN2211351 FACS IF IHC ELISA WB Biotin Rabbit IgG AA 28-59, N-Term Log in to see Polyclonal 0
1 ABIN865454 IF IHC ELISA WB Mouse IgG1 Log in to see 3F6 0

General

Antigen Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus), Monkey
(155), (77), (54), (13), (3), (2)
Host Mouse
(102), (47), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BMPR2 antibody is un-conjugated
(7), (6), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(117), (80), (78), (36), (31), (22), (13), (13), (5), (3), (3), (1)
Pubmed 2 references available
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Product Details anti-BMPR2 Antibody

Target Details BMPR2 Application Details Handling References for anti-BMPR2 antibody (ABIN965687) Images
Purification Ascitic fluid
Immunogen Purified recombinant fragment of human BMPR2 expressed in E. Coli.
Clone 3F6
Isotype IgG1
Plasmids, Primers & others

Target Details BMPR2

Product Details anti-BMPR2 Antibody Application Details Handling References for anti-BMPR2 antibody (ABIN965687) Images back to top
Antigen
Alternative Name BMPR2 (BMPR2 Antibody Abstract)
Background This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
Synonyms: BMR2, PPH1, BMPR3, BRK-3, TALK, BMPR-II, FLJ41585, FLJ76945, BMPR2
Molecular Weight 115kDa
Gene ID 659
Pathways Growth Factor Binding

Application Details

Product Details anti-BMPR2 Antibody Target Details BMPR2 Handling References for anti-BMPR2 antibody (ABIN965687) Images back to top
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Product Details anti-BMPR2 Antibody Target Details BMPR2 Application Details References for anti-BMPR2 antibody (ABIN965687) Images back to top
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C

References for anti-BMPR2 antibody (ABIN965687)

Product Details anti-BMPR2 Antibody Target Details BMPR2 Application Details Handling Images back to top
Product cited in:

Phillips, Poling, Phillips, Stanton, Austin, Cogan, Wheeler, Yu, Newman, Dietz, Loyd: "Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension." in: Genetics in medicine : official journal of the American College of Medical Genetics, Vol. 10, Issue 5, pp. 359-65, 2008

Background publications

Rosenzweig, Morse, Knowles, Chada, Khan, Roberts, McElroy, Juskiw, Mallory, Rich, Diamond, Barst: "Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension." in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, Vol. 27, Issue 6, pp. 668-74, 2008