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anti-Mouse (Murine) IFT27 Antibodies:
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Human Polyclonal IFT27 Primary Antibody for ICC, IF - ABIN4349027
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Show all 2 Pubmed References
Cow (Bovine) Polyclonal IFT27 Primary Antibody for IHC, WB - ABIN2783325
Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: A genome annotation-driven approach to cloning the human ORFeome. in Genome biology 2004
Findings suggest that like IFT25, IFT27, even though not required for ciliogenesis in somatic cells, is essential for sperm flagella formation, sperm function, and male fertility in mice. IFT25 and IFT27 control sperm formation/function through many common mechanisms, but IFT25 has additional roles beyond IFT27.
The study implicates Ift27 in basal mechanosensation.
this study demonstrated an essential role of Ift27 in mediating hedgehog (show SHH Antibodies) signaling during follicular keratinocyte proliferation and differentiation but not the differentiation program of the interfollicular epidermis.
IFT27 prevents aggregation of nucleotide-free ARL6 in solution
Lztfl1 (show LZTFL1 Antibodies) accumulate to high levels in Ift27 mutant cilia.
Study coupled human genetics with functional validation in zebrafish and identified IFT27 as a novel BBS (show BBS2 Antibodies) gene (BBS19).
This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B. Characterization of the similar Chlamydomonas protein indicates a function in cell cycle control. Alternative splicing of this gene results in multiple transcript variants.
RAB, member of RAS oncogene family-like 4
, intraflagellar transport 27 homolog
, intraflagellar transport protein 27 homolog
, rab-like protein 4
, putative GTP-binding protein RAY-like