anti-Goat Potassium Channel Tetramerisation Domain Containing 11 antibody for Western Blotting

Recommended Potassium Channel Tetramerisation Domain Containing 11 Antibody (supplied by: Log in to see )

Antigen
Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) Antibodies
  • KCTD11
  • AF465352
  • Ren
  • C17orf36
  • KCASH1
  • REN
  • REN/KCTD11
  • potassium channel tetramerization domain containing 11
  • potassium channel tetramerisation domain containing 11
  • KCTD11
  • Kctd11
Epitope
N-Term
11
3
2
1
1
1
Reactivity
Cow (Bovine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
39
21
18
3
2
2
1
1
1
1
1
Host
Rabbit
24
15
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
27
16
13
5
1
Options
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Catalog No. ABIN2776370
$ 229.00
Plus shipping costs $45.00

General

Antigen Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) Antibodies
Epitope N-Term
(11), (3), (2), (1), (1), (1)
Reactivity Cow (Bovine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(39), (21), (18), (3), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(24), (15)
Clonality
Polyclonal
Conjugate Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(27), (16), (13), (5), (1)
Pubmed 1 reference available
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Product details

Target Details Application Details Handling References Images
Sequence RLGRLDLPRG YGETALLRAE ADFYQIRPLL DALRELEASQ GTPAPTAALL
Predicted Reactivity Cow: 100%, Goat: 90%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against KCTD11. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human KCTD11

Target Details

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Antigen
Alternative Name KCTD11 (KCTD11 Antibody Abstract)
Background The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor-promoting Hedgehog pathway in medulloblastoma.
Alias Symbols: C17orf36, MGC129844, REN, REN/KCTD11, KCASH1
Protein Interaction Partner: KCTD11, CUL3, HDAC1,
Protein Size: 232
Molecular Weight 26 kDa
Gene ID 147040
NCBI Accession NM_001002914, NP_001002914
UniProt Q693B1
Pathways Hedgehog Signaling

Application Details

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Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 232 AA

Restrictions For Research Use only

Handling

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Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

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Background publications

Di Marcotullio, Ferretti, De Smaele, Argenti, Mincione, Zazzeroni, Gallo, Masuelli, Napolitano, Maroder, Modesti, Giangaspero, Screpanti, Alesse, Gulino: "REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 29, pp. 10833-8, 2004

Images

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Supplier Images
Western Blotting (WB) image for anti-Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) (N-Term) antibody (ABIN2776370) WB Suggested Anti-KCTD11 Antibody Titration: 1.25ug/ml Positive Control: Jurkat ce...