anti-Human SUFUH antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SUFUH Antibody (supplied by: Log in to see )

Antigen
Suppressor of Fused Homolog (Drosophila) (SUFUH) Antibodies
  • CG6054
  • Dmel\\CG6054
  • SU(FU)
  • SUFU
  • Su(Fu)
  • SuFu
  • Sufu
  • su(fu)
  • sufu
  • Xsufu
  • sufuh
  • sufuxl
  • PRO1280
  • SUFUH
  • SUFUXL
  • Su(fu)
  • dre
  • fi39e05
  • wu:fi39e05
  • 2810026F04Rik
  • b2b273Clo
  • Suppressor of fused
  • SUFU negative regulator of hedgehog signaling L homeolog
  • SUFU negative regulator of hedgehog signaling
  • suppressor of fused homolog (Drosophila)
  • Su(fu)
  • sufu.L
  • SUFU
  • sufu
  • Sufu
Reactivity
Human, Mouse (Murine), Rat (Rattus)
69
39
34
7
7
7
7
4
3
3
3
3
2
1
1
Host
Rabbit
63
4
2
Clonality
Polyclonal
Conjugate
This SUFUH antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
43
22
14
12
12
7
3
2
2
2
1
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Catalog No. ABIN1386317
$ 306.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.12081 ABIN783266 IHC (p) Goat IgG AA 2-13 Log in to see Polyclonal 0
7 ABIN959031 IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN1407812 IHC (p) HRP Rabbit IgG Log in to see Polyclonal 0
1 ABIN1389919 IHC (p) Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN6244107 IHC (p) WB Mouse IgG1, kappa Log in to see 1783CT536-263-29 0

General

Antigen Suppressor of Fused Homolog (Drosophila) (SUFUH) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(69), (39), (34), (7), (7), (7), (7), (4), (3), (3), (3), (3), (2), (1), (1)
Host Rabbit
(63), (4), (2)
Clonality
Polyclonal
Conjugate This SUFUH antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(43), (22), (14), (12), (12), (7), (3), (2), (2), (2), (1)
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Product Details anti-SUFUH Antibody

Target Details SUFUH Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human SUFU
Isotype IgG
Plasmids, Primers & others

Target Details SUFUH

Product Details anti-SUFUH Antibody Application Details Handling Images back to top
Antigen
Alternative Name SUFU/Suppressor of Fused (SUFUH Antibody Abstract)
Background

Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A). Required for the proper formation of hair follicles and the control of epidermal differentiation (By similarity).

Subcellular location: Cytoplasm, Nucleus

Synonyms: SUFUH, SUFUXL, PRO1280, Suppressor of fused homolog, SUFU, UNQ650/PRO1280

Gene ID 51684
UniProt Q9UMX1
Pathways Hedgehog Signaling, Tube Formation, Maintenance of Protein Location

Application Details

Product Details anti-SUFUH Antibody Target Details SUFUH Handling Images back to top
Application Notes IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-SUFUH Antibody Target Details SUFUH Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-SUFUH Antibody Target Details SUFUH Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Suppressor of Fused Homolog (Drosophila) (SUFUH) antibody (ABIN1386317) Lane 1:Mouse intestine lysate Lane 2: Mouse lung lysate Lane 3: Mouse brain probed wi...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Suppressor of Fused Homolog (Drosophila) (SUFUH) antibody (ABIN1386317) Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-SUFU/Suppressor o...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Suppressor of Fused Homolog (Drosophila) (SUFUH) antibody (ABIN1386317) Formalin-fixed and paraffin embedded rat brain labeled with Anti-SUFU/Suppressor of F...