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HNF1 Homeobox B Products

(HNF1 Homeobox B (HNF1B))

Categories

This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].

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Featured HNF1 Homeobox B Categories

HNF1 Homeobox B Antibodies

High quality antibodies with extensive validation data.

HNF1 Homeobox B ELISA Kits

Reliable ELISA kits for a wide range of species.

HNF1 Homeobox B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HNF1 Homeobox B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN520767
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN520762
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
  • (4)
Cat. No. ABIN2777700
Quantity 100 μL
Datasheet Datasheet

Recommended HNF1 Homeobox B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967453
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956590
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956591
Quantity 96 tests
Datasheet Datasheet

Recommended HNF1 Homeobox B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123355
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2565077
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306851
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our HNF1 Homeobox B products

Goyeneche, Koch, Bell, Telleria: "Long-term primary culture of a clear cell ovarian carcinoma reveals an epithelial-mesenchymal cooperative interaction." in: Cancer cell international, Vol. 15, pp. 88, (2015) (PubMed).

Debiais-Delpech, Godet, Pedretti, Bernard, Irani, Cathelineau, Cussenot, Fromont: "Expression patterns of candidate susceptibility genes HNF1? and CtBP2 in prostate cancer: association with tumor progression." in: Urologic oncology, Vol. 32, Issue 4, pp. 426-32, (2014) (PubMed).

Davidson: "Hepatocyte nuclear factor-1β is not a specific marker of clear cell carcinoma in serous effusions." in: Cancer cytopathology, Vol. 122, Issue 2, pp. 153-8, (2014) (PubMed).

Simeonov, Uppal: "Direct reprogramming of human fibroblasts to hepatocyte-like cells by synthetic modified mRNAs." in: PLoS ONE, Vol. 9, Issue 6, pp. e100134, (2014) (PubMed).

Donthamsetty, Bhave, Mars, Bowen, Orr, Haynes, Wu, Michalopoulos: "Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis." in: PLoS ONE, Vol. 8, Issue 9, pp. e74625, (2013) (PubMed).

Szponar, Yusenko, Kuiper, van Kessel, Kovacs: "Genomic profiling of papillary renal cell tumours identifies small regions of DNA alterations: a possible role of HNF1B in tumour development." in: Histopathology, Vol. 58, Issue 6, pp. 934-43, (2011) (PubMed).

Hakonarson, Qu, Bradfield, Marchand, Kim, Glessner, Grabs, Casalunovo, Taback, Frackelton, Eckert, Annaiah, Lawson, Otieno, Santa, Shaner, Smith, Onyiah, Skraban, Chiavacci, Robinson, Stanley, Kirsch et al.: "A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. ..." in: Diabetes, Vol. 57, Issue 4, pp. 1143-6, (2008) (PubMed).

Arenas, Hervias, Uriz, Joplin, Prieto, Medina: "Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells." in: The Journal of clinical investigation, Vol. 118, Issue 2, pp. 695-709, (2008) (PubMed).

Terasawa, Toyota, Sagae, Ogi, Suzuki, Sonoda, Akino, Maruyama, Nishikawa, Imai, Shinomura, Saito, Tokino: "Epigenetic inactivation of TCF2 in ovarian cancer and various cancer cell lines." in: British journal of cancer, Vol. 94, Issue 6, pp. 914-21, (2006) (PubMed).

Soubt, Marksitzer, Menoud, Nagamine: "Role of tissue-specific transcription factor LFB3 in a cyclic AMP-responsive enhancer of the urokinase-type plasminogen activator gene in LLC-PK1 cells." in: Molecular and cellular biology, Vol. 18, Issue 8, pp. 4698-706, (1998) (PubMed).

Synonyms and alternative names related to HNF1 Homeobox B

HNF1 homeobox B (HNF1B), HNF1 homeobox B (Hnf1b), HNF1 homeobox Ba (hnf1ba), HNF1 homeobox B S homeolog (hnf1b.S), HNF1 homeobox B L homeolog (hnf1b.L), HNF1 homeobox Bb (hnf1bb), AI385728, AI987804, chunp6877, FJHN, HNF-1B, HNF-1b, HNF-1Beta, hnf-1beta, hnf1-beta, HNF1B, hnf1b, HNF1beta, Hnf1beta, hnf1beta, HNF1g, HNF2, HPC11, LF-B3, LFB3, lfb3, MODY5, mst, TCF-2, Tcf-2, TCF2, Tcf2, tcf2, vHNF-1, VHNF1, vHNF1, vhnf1, wu:fc23f06

Protein level used designations for HNF1 Homeobox B

  • HNF-1-beta
  • HNF1 beta A
  • hepatocyte nuclear factor 1-beta
  • homeoprotein LFB3
  • transcription factor 2, hepatic
  • hepatocyte nuclear factor 1 beta
  • transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor
  • HNF1 homeobox B
  • HNF-1B
  • hepatocyte nuclear factor-1 beta
  • transcription factor 2
  • TCF-2
  • Transcription factor 2 hepatic
  • Transcription factor 2 hepatic; LF-B3; variant hepatic nuclear factor
  • Transcription factor 2, hepatic
  • Transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor
  • variant hepatic nuclear factor 1
  • FPC-binding protein
  • FPCB
  • HNF-1-beta-A
  • HNF-1B-2
  • HNF-1B-A
  • HNF1 homeobox b
  • hepatocyte nuclear factor 1-beta-2
  • hepatocyte nuclear factor 1-beta-A
  • hob
  • xlFB3
  • HNF-1-beta-B
  • HNF-1B-B
  • hepatocyte nuclear factor 1-beta-B
  • hepatocyte nuclear factor 1-gamma
  • hnf1bl
  • hnf1gamma
  • liver-enriched atypical homeobox-containing transcription factor
  • transcription factor 2 like protein
  • HNF-1 beta
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