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|Antigen||Brain Natriuretic Peptide (BNP) Antibodies|
|Conjugate||This BNP antibody is un-conjugated Alternatives|
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Product Details anti-BNP AntibodyTarget Details BNP Application Details Handling Images
|Immunogen||Synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP1|
|Plasmids, Primers & others|
Target Details BNPProduct Details anti-BNP Antibody Application Details Handling Images back to top
|Alternative Name||BNP1 (BNP Antibody Abstract)|
|Background||BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.|
Application DetailsProduct Details anti-BNP Antibody Target Details BNP Handling Images back to top
IHC(P):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
|Restrictions||For Research Use only|
HandlingProduct Details anti-BNP Antibody Target Details BNP Application Details Images back to top
|Handling Advice||As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.|
|Storage Comment||BNP1 monoclonal antibody can be stored at -20 °C, stable for one year.|
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