anti-Mouse (Murine) CGRP antibody for Enzyme Immunoassay

Recommended CGRP Antibody (supplied by: Log in to see )

Antigen
Calcitonin-Related Polypeptide alpha (CALCA) Antibodies
  • CALC1
  • CGRP
  • CGRP-I
  • CGRP1
  • CT
  • KC
  • CALC
  • CALCA
  • CALC3
  • ci-ct
  • calca
  • CA
  • CGRP-1
  • Calc
  • Calc1
  • Cgrp
  • Ct
  • Ctn
  • calcitonin
  • CAL6
  • Cal1
  • RATCAL6
  • CGRPI
  • calc
  • cgrp
  • zgc:92886
  • calcitonin related polypeptide alpha
  • calcitonin related polypeptide beta
  • calcitonin-related polypeptide alpha
  • calcitonin
  • calcitonin/calcitonin-related polypeptide, alpha
  • calcitonin gene-related peptide 2
  • CALCA
  • CALCB
  • ci-ct
  • calca
  • Calca
  • LOC100008771
Epitope
AA 23-37
17
15
5
4
3
2
2
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus), Reptile
119
92
33
3
2
2
1
1
1
1
1
1
1
1
1
Host
Goat
80
51
10
8
3
Clonality
Polyclonal
Conjugate
This CGRP antibody is un-conjugated
11
7
7
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
76
66
54
49
31
21
15
13
10
8
7
5
3
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN112616
$ 390.50
Plus shipping costs $45.00

General

Antigen Calcitonin-Related Polypeptide alpha (CALCA) Antibodies
Epitope AA 23-37
(17), (15), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine), Rat (Rattus), Reptile
(119), (92), (33), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host Goat
(80), (51), (10), (8), (3)
Clonality
Polyclonal
Conjugate This CGRP antibody is un-conjugated
(11), (7), (7), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(76), (66), (54), (49), (31), (21), (15), (13), (10), (8), (7), (5), (3), (1)
Pubmed 7 references available
Supplier Log in to see

Product Details anti-CGRP Antibody

Target Details CGRP Application Details Handling References for anti-CGRP antibody (ABIN112616) Images
Specificity Recognizes Calcitonin gene-related peptide, also known as CGRP, a neuropeptide that acts as a vasodilator and may play a role in migraine. This antibody is reactive with both whole molecule (1-37) and the C-terminal (23-37). Specifically visualises CGRP in brain cells.
Purification Affinity Chromatography on Protein G
Immunogen Synthetic Rat Tyr-CGRP (23-37) conjugated to gamma globulin
Isotype IgG
Plasmids, Primers & others

Target Details CGRP

Product Details anti-CGRP Antibody Application Details Handling References for anti-CGRP antibody (ABIN112616) Images back to top
Antigen
Alternative Name CGRP / CALCA (CALCA Antibody Abstract)
Background CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat, it can modulate acetylcholine receptor function at the neuromuscular junction, it has been demonstrated to block tolerance to morphine, and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.Synonyms: Alpha-type CGRP, CALC1, CGRP-I, Calcitonin gene-related peptide I
Gene ID 24241
NCBI Accession NP_001029127
UniProt P01256
Pathways Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour

Application Details

Product Details anti-CGRP Antibody Target Details CGRP Handling References for anti-CGRP antibody (ABIN112616) Images back to top
Application Notes ELISA (1/500-1/2500). Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CGRP Antibody Target Details CGRP Application Details References for anti-CGRP antibody (ABIN112616) Images back to top
Format Liquid
Concentration 5.0 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CGRP antibody (ABIN112616)

Product Details anti-CGRP Antibody Target Details CGRP Application Details Handling Images back to top
Background publications

Hamed, Giles, Anderson, Phillips, Dawson, Drummond, Wallace, Wood, Rea, Fear: "Changes in cutaneous innervation in patients with chronic pain after burns." in: Burns : journal of the International Society for Burn Injuries, Vol. 37, Issue 4, pp. 631-7, 2011

Gnanamanickam, Llewellyn-Smith: "Innervation of the rat uterus at estrus: a study in full-thickness, immunoperoxidase-stained whole-mount preparations." in: The Journal of comparative neurology, Vol. 519, Issue 4, pp. 621-43, 2011

Fan, Bouwense, Crawford, Xiao: "Structural and cellular features in metaphyseal and diaphyseal periosteum of osteoporotic rats." in: Journal of molecular histology, Vol. 41, Issue 1, pp. 51-60, 2010

Brock, Handelsman, Keast: "Postnatal androgen deprivation dissociates the development of smooth muscle innervation from functional neurotransmission in mouse vas deferens." in: The Journal of physiology, Vol. 581, Issue Pt 2, pp. 665-78, 2007

Collins, Wilson, Fischer-Colbrie, Papka: "Distribution and origin of secretoneurin-immunoreactive nerves in the female rat uterus." in: Neuroscience, Vol. 95, Issue 1, pp. 255-64, 2000

Pritz, Stritzel: "Reptilian dorsal column nucleus lacks GAD immunoreactive neurons." in: Brain research, Vol. 503, Issue 1, pp. 175-9, 1990

Pritz, Stritzel: "Thalamic nuclei that project to reptilian telencephalon lack GABA and GAD immunoreactive neurons and puncta." in: Brain research, Vol. 457, Issue 1, pp. 154-9, 1988

Images

Product Details anti-CGRP Antibody Target Details CGRP Application Details Handling References for anti-CGRP antibody (ABIN112616) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 23-37) antibody (ABIN112616) Paraffin embedded rat intestine stained with goat anti rat CGRP antibody ABIN112616