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|Antigen||Calcitonin-Related Polypeptide alpha (CALCA) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Host||Guinea Pig Alternatives|
|Conjugate||This CGRP antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Product Details anti-CGRP AntibodyTarget Details CGRP Application Details Handling Images
|Cross-Reactivity (Details)||Recognizes human, rat, and mouse. Does not cross-react with amylin (IAPP).200 ug/mlPositive control: Frozen sections of rat colon.|
|Immunogen||CGRP antibody was raised in guinea pig using calcitonin gene-related peptide conjugated to BSA as the immunogen.|
|Plasmids, Primers & others|
Target Details CGRPProduct Details anti-CGRP Antibody Application Details Handling Images back to top
|Alternative Name||CGRP (CALCA Antibody Abstract)|
|Background||The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP. Absorption with 10 – 100 ug CGRP per ml diluted antiserum abolishes the staining while calcitonin does not. Does not cross-react with amylin (IAPP).|
|Pathways||Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour|
Application DetailsProduct Details anti-CGRP Antibody Target Details CGRP Handling Images back to top
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CGRP Antibody Target Details CGRP Application Details Images back to top
|Buffer||Dissolve the antiserum in 50 - 100 µL distilled water, and dilute further in 0.1 M PBS with 1 % BSA and 0.1 % NaN3.|
|Precaution of Use||This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.|