anti-Human DIO1 antibody for Western Blotting

Recommended DIO1 Antibody (supplied by: Log in to see )

Antigen
Deiodinase, Iodothyronine, Type I (DIO1) Antibodies
  • 5DI
  • TXDI1
  • ITDI1
  • D1
  • DIOI
  • Deio1
  • cb685
  • zgc:92323
  • iodothyronine deiodinase 1
  • type I iodothyronine deiodinase-like
  • deiodinase, iodothyronine, type I
  • deiodinase, iodothyronine type 1 L homeolog
  • DIO1
  • LOC100231867
  • Dio1
  • dio1.L
  • dio1
Epitope
AA 30-57, N-Term
12
9
9
3
1
Reactivity
Human
25
3
2
Host
Rabbit
23
3
Clonality
Polyclonal
Conjugate
This DIO1 antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
22
18
2
2
1
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Catalog No. ABIN390946
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2307212 ABIN5533453 WB Rabbit Ig Fraction AA 30-57, N-Term Log in to see Polyclonal 0
3.2307212 ABIN4903484 WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN452912 EIA WB Rabbit N-Term, AA 36-66 Log in to see Polyclonal 0
1 ABIN1962678 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 30-57 Log in to see Polyclonal 0
1 ABIN1969151 ELISA WB Biotin Rabbit IgG AA 30-57 Log in to see Polyclonal 0
1 ABIN1971469 ELISA WB FITC Rabbit IgG AA 30-57 Log in to see Polyclonal 0
1 ABIN1965055 ELISA WB APC Rabbit IgG AA 30-57 Log in to see Polyclonal 0
1 ABIN1976068 ELISA WB PE Rabbit IgG AA 30-57 Log in to see Polyclonal 0
1 ABIN2598494 ELISA WB Rabbit IgG AA 36-66 Log in to see Polyclonal 0
1 ABIN2253475 ELISA WB Rabbit IgG N-Term, AA 36-66 Log in to see Polyclonal 0
1 ABIN1973025 ELISA WB HRP Rabbit IgG AA 30-57 Log in to see Polyclonal 0
1 ABIN2253480 ELISA WB FITC Rabbit IgG N-Term, AA 36-66 Log in to see Polyclonal 0
1 ABIN2253479 ELISA WB PE Rabbit IgG N-Term, AA 36-66 Log in to see Polyclonal 0
1 ABIN2253477 ELISA WB APC Rabbit IgG N-Term, AA 36-66 Log in to see Polyclonal 0
1 ABIN2253481 ELISA WB HRP Rabbit IgG N-Term, AA 36-66 Log in to see Polyclonal 0
1 ABIN1813574 WB Rabbit AA 30-57 Log in to see Polyclonal 0
1 ABIN2253478 ELISA WB Biotin Rabbit IgG N-Term, AA 36-66 Log in to see Polyclonal 0
1 ABIN2253476 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG N-Term, AA 36-66 Log in to see Polyclonal 0
1 ABIN5699969 ELISA IHC IP WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2795104 WB Rabbit Ig Fraction N-Term Log in to see Polyclonal 0

General

Antigen Deiodinase, Iodothyronine, Type I (DIO1) Antibodies
Epitope AA 30-57, N-Term
(12), (9), (9), (3), (1)
Reactivity Human
(25), (3), (2)
Host Rabbit
(23), (3)
Clonality (Clone)
Polyclonal   ( )
Conjugate This DIO1 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Western Blotting (WB)
(22), (18), (2), (2), (1)
Pubmed 1 reference available
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Product Details anti-DIO1 Antibody

Target Details DIO1 Application Details Handling References for anti-DIO1 antibody (ABIN390946) Images
Specificity This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36~66 amino acids from the N-terminal region of human DIO1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 AA from the N-terminal region of human DIO1.
Clone RB21147
Isotype Ig Fraction

Target Details DIO1

Product Details anti-DIO1 Antibody Application Details Handling References for anti-DIO1 antibody (ABIN390946) Images back to top
Antigen
Alternative Name DIO1 (DIO1 Antibody Abstract)
Background DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD).
Synonyms: Type I iodothyronine deiodinase, Type-I 5'-deiodinase, Type 1 DI, DIOI, 5DI, TXDI1, ITDI1, DIO1
Molecular Weight 28924 DA
Gene ID 1733
UniProt P49895
Pathways Hormone Activity

Application Details

Product Details anti-DIO1 Antibody Target Details DIO1 Handling References for anti-DIO1 antibody (ABIN390946) Images back to top
Application Notes WB = 1:1000
Restrictions For Research Use only

Handling

Product Details anti-DIO1 Antibody Target Details DIO1 Application Details References for anti-DIO1 antibody (ABIN390946) Images back to top
Format Liquid
Concentration 0.315 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-DIO1 antibody (ABIN390946)

Product Details anti-DIO1 Antibody Target Details DIO1 Application Details Handling Images back to top
Background publications

Landa, Ruiz-Llorente, Montero-Conde, Inglada-Pérez, Schiavi, Leskelä, Pita, Milne, Maravall, Ramos, Andía, Rodríguez-Poyo, Jara-Albarrán, Meoro, del Peso, Arribas, Iglesias, Caballero, Serrano, Picó, Pomares, Giménez, López-Mondéjar, Castello, Merante-Bos: "The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors." in: PLoS genetics, Vol. 5, Issue 9, pp. e1000637, 2009

Images

Product Details anti-DIO1 Antibody Target Details DIO1 Application Details Handling References for anti-DIO1 antibody (ABIN390946) back to top
Supplier Images
Western Blotting (WB) image for anti-Deiodinase, Iodothyronine, Type I (DIO1) (AA 30-57), (N-Term) antibody (ABIN390946) Western blot analysis of DIO1 Antibody (N-term) (ABIN390946) in HepG2 cell line lysat...