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CNP and BNP serve as oocyte maturation inhibitor to inhibit oocyte maturation in mammals
ANP and BNP gene expression differs considerably between cardiac chambers in the first 72 hours of life in healthy piglets, resembling the transition from fetal to neonate circulation. The cardiac gene expression does not explain plasma concentrations.
Up-regulation of BNP and a reduction in a ratio of sarcoplasmic reticulum calcium ATPase 2a in failing myocardium are observed in a porcine model of tachycardia.
serum levels predict mortality in chest pain patients in Argentina
Data show that all five molecules, BNP, ICAM-1, TNF-alpha, VCAM-1 and IL-6, quickly and reliably signaled adverse interactions.
identification and characterization of a novel alternatively spliced variant of porcine and human NPPB resulting from exon 2 skipping
Arial natriuretic factor (ANF) and N-terminal proANF may be better suited than brain natriuretic peptide as markers of cardiac preload during the development and treatment of acute heart failure.
Regional differences in BNP and CNP expression were observed in myocardium with sustained left ventricular dyssynchronous contraction.
This study showed that a higher plasma BNP was associated with a lower left atrial appendage flow velocity in patients with non-valvular atrial fibrillation and normal LV systolic function.
The inclusion of NT-proBNP to the 3C-HF and Seattle heart failure model score resulted in significantly better risk stratification.
In patients with acute exacerbation of COPD, average value of NT-proBNP in patients with left ventricular systolic dysfunction (LVSD) was 3303.2 vs. 1092.5 pg/mL in patients without LVSD.
The polymorphisms of BNP at the rs198389, rs6668352, and rs198388 loci are associated with the occurrence of COPD and COPD with PH, and the occurrence may be related to the abnormal expression level of BNP, Fbg, and Apelin protein in the serum.
increased circulating levels of sTNFR1 and BNP were associated with loss of kidney function in Type 2 diabetic Egyptian patients
Among 3,187 stable coronary artery disease patients with NT-proBNP data, after a 2-year follow-up, NT-proBNP levels were predictive for all-cause death in the stable coronary artery disease population
NTproBNP levels differed among infants who did and did not develop bronchopulmonary dysplasia from 14 to 35 days of life with the greatest difference on day 14 of life. The presence of patent ductus arteriosus did not account for higher levels of NTproBNP at day 14.
In patients with pulmonary arterial hypertension, there appears to be a trend of pro-BNP level increasing immediately after exercise and continuing to be elevated at 1 h. Pro-BNP levels then return to baseline at 2 h post 6 minute walk test.
NT-proANP and NT-proBNP show different sensitivity for phenotypes of atrial fibrillation progression.
Amino-terminal pro-brain natriuretic peptide serum level is associated with catheter-related bloodstream infection in severe burn patients.
BNP is increased in diabetic patients with acute heart failure.
In patients undergoing noncardiac thoracic surgery, we found that an elevated preoperative BNP level (with the level of 59 pg/mL as a cutoff), male gender, and open-chest surgeries were significant risk factors for postoperative atrial fibrillation.
B-type natriuretic peptide levels may predict prognosis in older adults admitted with a diagnosis other than heart failure.
Post-implant changes in NT-proBNP correlate with echocardiographic and clinical response to cardiac resynchronization therapy.
Serial measurement of NT-proBNP in patients with chronic heart failure improves prediction of all-cause mortality.
NT-proBNP predicts mortality in elderly and very elderly patients with chronic systolic heart failure.
Suggest that natriuretic peptides play a role in cholesterol metabolism, given the association found between LDLc and NT-proBNP even in very elderly patients where NT-proBNP values are often in the pathological range.
NT-proBNP and hs-cTnT are useful biomarkers in assessment of hypertrophy and fibrosis in hypertrophic cardiomyopathy.
Serum NT-proBNP may relate to severity and prognosis of cerebral stroke patients as shown by the Modified Rankin Scale
NT-proBNP is associated with all myocardial infarctions, but is a more powerful risk factor for microsize than typical MI.
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
gamma-brain natriuretic peptide
, natriuretic peptides B
, brain type natriuretic peptide
, natriuretic peptide precursor B
, natriuretic protein
, Brain natriuretic factor
, brain natriuretic peptide
, natriuretic peptide precursor type B
, Gamma-brain natriuretic peptide