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|Antigen||Stanniocalcin 2 (STC2) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Stanniocalcin 2 antibody is conjugated to HRP Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-Stanniocalcin 2 AntibodyTarget Details Stanniocalcin 2 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human Stanniocalcin 2|
Target Details Stanniocalcin 2Product Details anti-Stanniocalcin 2 Antibody Application Details Handling Images back to top
|Alternative Name||Stanniocalcin 2 (STC2 Antibody Abstract)|
Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumors, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumor cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells).
Synonyms: Stanniocalcin related protein, Stanniocalcin-2, Stanniocalcin-related protein, Stanniocalcin2, STC 2, STC related protein, STC-2, STC-related protein, STC2, STC2_HUMAN, STCRP.
|Pathways||Hormone Activity, ER-Nucleus Signaling|
Application DetailsProduct Details anti-Stanniocalcin 2 Antibody Target Details Stanniocalcin 2 Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-Stanniocalcin 2 Antibody Target Details Stanniocalcin 2 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.|
|Precaution of Use||This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|