IGF2R Products
(Insulin-Like Growth Factor 2 Receptor (IGF2R))
Categories
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq, Apr 2013].
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Featured IGF2R Categories
IGF2R Antibodies
High quality antibodies with extensive validation data.
IGF2R ELISA Kits
Reliable ELISA kits for a wide range of species.
IGF2R Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IGF2R Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Non-Human Primate
Application
WB, FACS, IP
Validations
- (2)
- (4)
Cat. No.
ABIN94039
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN7267905
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (1)
- (5)
Cat. No.
ABIN5693085
Quantity
100 μg
Datasheet
Datasheet
Recommended IGF2R ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967650
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956801
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN2859333
Quantity
96 tests
Datasheet
Datasheet
Recommended IGF2R Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123457
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307559
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3083855
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our IGF2R products
: "The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease." in: Acta neuropathologica communications, Vol. 7, Issue 1, pp. 13, (2019) (PubMed).: "Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells." in: Stem cells (Dayton, Ohio), Vol. 37, Issue 8, pp. 1030-1041, (2019) (PubMed).
: "Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning." in: Neuron, Vol. 99, Issue 5, pp. 985-998.e6, (2018) (PubMed).
: "Enhanced suppression of polyclonal CD8+25+regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes." in: Journal of leukocyte biology, Vol. 101, Issue 5, pp. 1221-1231, (2017) (PubMed).
: "mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A." in: Cell discovery, Vol. 3, pp. 17011, (2017) (PubMed).
: "CD44+fibroblasts increases breast cancer cell survival and drug resistance via IGF2BP3-CD44-IGF2 signalling." in: Journal of cellular and molecular medicine, Vol. 21, Issue 9, pp. 1979-1988, (2017) (PubMed).
: "IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids." in: Redox biology, Vol. 13, pp. 69-81, (2017) (PubMed).
: "Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models." in: Scientific reports, Vol. 7, Issue 1, pp. 2817, (2017) (PubMed).
: "The association of soluble IGF2R and IGF2R gene polymorphism with type 2 diabetes." in: Journal of diabetes research, Vol. 2015, pp. 216383, (2015) (PubMed).
: "Rapid multiplex analysis of lipid raft components with single-cell resolution." in: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).
Synonyms and alternative names related to IGF2R
insulin like growth factor 2 receptor (IGF2R), insulin-like growth factor 2 receptor (Igf2r), insulin like growth factor 2 receptor (igf2r), AI661837, CD222, cd222, CI-MPR, CIMPR, cimpr, M6P-R, m6p-r, M6P/IGF2R, MPR1, Mpr300, MPRI, mpriProtein level used designations for IGF2R
- 300 kDa mannose 6-phosphate receptor
- CI Man-6-P receptor
- CI-MPR
- IGF-II receptor
- M6P/IGF2 receptor
- M6P/IGF2R
- M6PR
- MPR 300
- cation-independent mannose-6 phosphate receptor
- cation-independent mannose-6-phosphate receptor
- insulin-like growth factor II receptor
- IGF-II/CI-MPR
- cation-independent MPR
- cation-independent mannose 6-phosphate receptor
- mannose-6-phosphate receptor, cation independent
- insulin-like growth factor receptor type 2
- cation-independent mannose 6 phosphate receptor
- insulin-like growth factor 2 receptor
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