Influenza Nucleoprotein Products
(Influenza Nucleoprotein (NP))
Categories
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus (By similarity).
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Featured Influenza Nucleoprotein Categories
Influenza Nucleoprotein Antibodies
High quality antibodies with extensive validation data.
Influenza Nucleoprotein Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Influenza Nucleoprotein Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Influenza A Virus H2N2
Application
ELISA, WB, IF, IHC, IP, IC
Validations
- (3)
- (4)
Cat. No.
ABIN2452039
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Influenza A Virus H2N2
Application
ELISA, WB, IHC, IC
Validations
- (3)
- (3)
Cat. No.
ABIN2452038
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Influenza B Virus
Application
ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN5707182
Quantity
1 mL
Datasheet
Datasheet
Recommended Influenza Nucleoprotein Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Influenza B Virus
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7385956
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Influenza A Virus
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7385954
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Influenza A Virus
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7519580
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Influenza Nucleoprotein products
: "FKBP5 Regulates RIG-I-Mediated NF-κB Activation and Influenza A Virus Infection." in: Viruses, Vol. 12, Issue 6, (2020) (PubMed).: "Morin Hydrate Inhibits Influenza Virus entry into Host Cells and Has Anti-inflammatory Effect in Influenza-infected Mice." in: Immune network, Vol. 20, Issue 4, pp. e32, (2020) (PubMed).
: "New MoDC-Targeting TNF Fusion Proteins Enhance Cyclic Di-GMP Vaccine Adjuvanticity in Middle-Aged and Aged Mice." in: Frontiers in immunology, Vol. 11, pp. 1674, (2020) (PubMed).
: "Lung IFNAR1hi TNFR2+ cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state." in: Mucosal immunology, Vol. 13, Issue 4, pp. 595-608, (2020) (PubMed).
: "Inducible Bronchus-Associated Lymphoid Tissues (iBALT) Serve as Sites of B Cell Selection and Maturation Following Influenza Infection in Mice." in: Frontiers in immunology, Vol. 10, pp. 611, (2020) (PubMed).
: "Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins." in: Nature communications, Vol. 7, pp. 12754, (2018) (PubMed).
: "Inactivated H7 Influenza Virus Vaccines Protect Mice despite Inducing Only Low Levels of Neutralizing Antibodies." in: Journal of virology, Vol. 91, Issue 20, (2017) (PubMed).
: "Simulated Respiratory Secretion for Use in the Development of Influenza Diagnostic Assays." in: PLoS ONE, Vol. 11, Issue 11, pp. e0166800, (2017) (PubMed).
: "Synergistic effect of nitazoxanide with neuraminidase inhibitors against influenza A viruses in vitro." in: Antimicrobial agents and chemotherapy, Vol. 59, Issue 2, pp. 1061-9, (2015) (PubMed).
: "Pathogenesis of novel reassortant avian influenza virus A (H5N8) Isolates in the ferret." in: Virology, Vol. 481, pp. 136-41, (2015) (PubMed).
Synonyms and alternative names related to Influenza Nucleoprotein
nucleoprotein (NP)Did you look for something else?
- Influenza Hemagglutinin HA2 Chain
- Influenza Hemagglutinin HA1 Chain
- Influenza B Virus Neuraminidase
- Influenza A Virus NS2
- Influenza A Virus Neuraminidase
- Influenza A Virus Matrix Protein 1
- Influenza A Virus H5N1
- Influenza A Virus H3N2
- Influenza A NS1
- Influenza A Matrix Protein 2
- Influenza A H1N1 PB1
- Infliximab
- INF2
- INE1
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
- Indoleacetic Acid
- Indole 3 Acetic Acid
- Indian Hedgehog
- INCE
- INCC
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