anti-Rat (Rattus) MTM1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended MTM1 Antibody (supplied by: Log in to see )

Antigen
Myotubularin 1 (MTM1) Antibodies
  • wu:fb19c01
  • zgc:123266
  • CNM
  • MTMX
  • XLMTM
  • AF073996
  • Mtm
  • mKIAA4176
  • myotubularin 1
  • X-linked myotubular myopathy gene 1
  • MTM1
  • mtm1
  • Mtm1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
77
48
24
5
3
2
2
1
1
1
1
Host
Rabbit
65
9
4
Clonality
Polyclonal
Conjugate
This MTM1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
57
33
15
12
10
3
2
1
1
1
Options
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Available images

Catalog No. ABIN1386965
$ 295.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2804352 IF (p) Alexa Fluor 594 Rabbit IgG Log in to see Polyclonal
1 ABIN1401287 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN1401285 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal
1 ABIN1401286 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN1401288 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN1401290 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN1419155 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN1419157 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN1419158 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN1419156 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN5007106 IF (p) Alexa Fluor 680 Rabbit IgG Log in to see Polyclonal
1 ABIN5007107 IF (p) Alexa Fluor 750 Rabbit IgG Log in to see Polyclonal

General

Antigen Myotubularin 1 (MTM1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(77), (48), (24), (5), (3), (2), (2), (1), (1), (1), (1)
Host Rabbit
(65), (9), (4)
Clonality
Polyclonal
Conjugate This MTM1 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(57), (33), (15), (12), (10), (3), (2), (1), (1), (1)
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Product Details anti-MTM1 Antibody

Target Details MTM1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human MTM1/Myotubularin
Isotype IgG

Target Details MTM1

Product Details anti-MTM1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MTM1 (MTM1 Antibody Abstract)
Background

X-linked recessive myotubular myopathy is a congenital muscular disease characterized by severe hypotonia and generalized muscle weakness that, in most cases, leads to early postnatal death. The gene responsible for myotubular myopathy MTM1 encodes a dual specificity phosphatase, named myotubularin, which is highly conserved through evolution. The gene for MTM1 is localized to a 300 kb critical region on human Xq128 between IDS and GRBRA3. Human MTM1, a 603 amino-acid protein, is mutated in myotubular myopathy. The largely related protein hMTMR2 is found mutated in a recessive form of Charcot-Marie-Tooth neuropathy. Myotubularin is primarily a lipid phosphatase that acts on phosphatidylinositol 3-monophosphate and is involved in the regulation of the phosphatidylinositol 3-kinase (PI3-kinase) pathway and membrane trafficking. Wild-type myotubularin can directly dephosphorylate PI3P and PI4P in vitro. Thus, it decreases PI3P levels by down-regulating PI3K activity and by facilitating the degradation of PI3P.

Synonyms: CG2, CNM, KIAA4176, mKIAA4176, Mtm, Mtm1, MTM1_HUMAN, MTMX, Myotubular myopathy 1, Myotubularin, XLMTM.

Gene ID 4534
Research Area Stem Cells, Metabolism
Pathways Inositol Metabolic Process, Skeletal Muscle Fiber Development

Application Details

Product Details anti-MTM1 Antibody Target Details MTM1 Handling Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-MTM1 Antibody Target Details MTM1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-MTM1 Antibody Target Details MTM1 Application Details Handling back to top
Supplier Images
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) image for anti-Myotubularin 1 (MTM1) antibody (ABIN1386965) Paraformaldehyde-fixed, paraffin embedded Rat colon; Antigen retrieval by boiling in ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Myotubularin 1 (MTM1) antibody (ABIN1386965) Paraformaldehyde-fixed, paraffin embedded Mouse stomach; Antigen retrieval by boiling...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Myotubularin 1 (MTM1) antibody (ABIN1386965) Paraformaldehyde-fixed, paraffin embedded Human cervical carcinoma; Antigen retrieval...