anti-Non-Human Primate Integrin alpha 4 antibody for Immunohistochemistry (Formalin-fixed Sections)

Recommended Integrin alpha 4 Antibody

Antigen
Integrin alpha 4 (ITGA4) Antibodies
  • CD49D
  • IA4
  • LOC100219853
  • integrin subunit alpha 4
  • integrin alpha 4
  • integrin subunit alpha 4 S homeolog
  • ITGA4
  • Itga4
  • itga4.S
Reactivity
Cat (Feline), Cow (Bovine), Dog (Canine), Horse (Equine), Human, Non-Human Primate, Sheep (Ovine)
339
240
107
20
13
12
11
9
8
8
7
3
3
3
2
2
2
2
2
2
1
1
1
1
Host
Mouse
175
154
144
1
1
Clonality
Monoclonal
Conjugate
Un-conjugated
58
57
32
12
10
7
7
5
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS)
323
122
113
99
64
40
34
31
22
13
7
6
6
4
4
3
3
2
2
1
1
Options
Catalog No. ABIN2967175
$ 343.07
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
13.447434 ABIN2967176 Func IHC (f) FACS Mouse IgG1 9F10 0
13.447434 ABIN2869980 Func IHC (f) FACS PE Mouse IgG1 9F10 0
13.447434 ABIN6579824 FACS Func IHC (f) FITC Mouse IgG1 9F10 0

General

Antigen Integrin alpha 4 (ITGA4) Antibodies
Reactivity Cat (Feline), Cow (Bovine), Dog (Canine), Horse (Equine), Human, Non-Human Primate, Sheep (Ovine)
(339), (240), (107), (20), (13), (12), (11), (9), (8), (8), (7), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(175), (154), (144), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate Un-conjugated
(58), (57), (32), (12), (10), (7), (7), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS)
(323), (122), (113), (99), (64), (40), (34), (31), (22), (13), (7), (6), (6), (4), (4), (3), (3), (2), (2), (1), (1)
Supplier

Product details

Target Details Application Details Handling Images
Specificity The mouse monoclonal antibody 9F10 recognizes CD49d (alpha 4 integrin), a 145-180 kDa type I transmembrane glycoprotein expressed on B and T cells, monocytes, eosinophils, basophils, NK cells, and dendritic cells, but not platelets.
HLDA V, WS Code S215
Cross-Reactivity (Details) Human, Non-Human Primates, Bovine, Canine (Dog), Equine (Horse), Feline (Cat), Sheep
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Sterility 0.2 μm filtered
Endotoxin Level Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
Clone 9F10
Isotype IgG1

Target Details

Product details Application Details Handling Images back to top
Antigen
Alternative Name CD49d / Integrin alpha 4 (ITGA4 Antibody Abstract)
Background CD49d / integrin alpha 4, unlike other alpha integrins, neither contains an I-domain, nor undergoes disulfide-linked cleavage. It associates with beta 7 chain to form alpha 4 / beta 7 integrin, and with beta 1 chain (CD29) to form VLA-4 integrin. These complexes are important for lymphocyte migration from circulation into tissue (binding VCAM-1) and homing of T cell subsets to Peyer´s patches (binding MadCAM-1), but VLA-4 is also target for invasive bacteria which contain invasin. CD49d is essential for differentiation and migration of hematopoietic stem cells by their adhesion to bone marrow stromal cells, and provides a costimulatory signal to TCR-CD3 complex by inducing phosphorylation of some focal adhesion proteins.
Gene ID 3676
Pathways Integrin Complex

Application Details

Product details Target Details Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product details Target Details Application Details Images back to top
Buffer Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μ,m filter sterilized.
Preservative Azide free
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.