Browse our anti-Death-Domain Associated Protein (DAXX) Antibodies

Full name:: anti-Death-Domain Associated Protein Antibodies (DAXX)

On www.antibodies-online.com are 322 Death-Domain Associated Protein (DAXX) Antibodies from 25 different suppliers available. Additionally we are shipping Death-Domain Associated Protein Kits (35) and Death-Domain Associated Protein Proteins (9) and many more products for this protein. A total of 383 Death-Domain Associated Protein products are currently listed.

Synonyms:: BING2, DAP6, daxx, EAP1, im:6905684, LOC100226911, si:dz179b20.7, wu:fd15c03

list all antibodies	Gene Name	GeneID	UniProt
	DAXX	1616	Q9UER7
	DAXX	13163	O35613
	DAXX	140926
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Intracellular Steroid Hormone Receptor Signaling Pathway

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Top referenced anti-Death-Domain Associated Protein Antibodies

Human Polyclonal DAXX Primary Antibody for ICC, IF - ABIN4304326 : Stepp, Meyers, McBride: Sp100 provides intrinsic immunity against human papillomavirus infection. in mBio 2013 (PubMed)
Show all 8 Pubmed References
Human Monoclonal DAXX Primary Antibody for IHC (fro), WB - ABIN2473232 : Barnes: Toxicity equivalents and EPA's risk assessment of 2,3,7,8-TCDD. in The Science of the total environment 1991 (PubMed)
Show all 4 Pubmed References
Human Monoclonal DAXX Primary Antibody for FACS, IF - ABIN965974 : Yang, Khosravi-Far, Chang, Baltimore: Daxx, a novel Fas-binding protein that activates JNK and apoptosis. in Cell 1997 (PubMed)
Show all 3 Pubmed References
Human Monoclonal DAXX Primary Antibody for ICC, WB - ABIN94302 : Leal-Sanchez, Couzinet, Rossin, Abdel-Sater, Chakrabandhu, Luci, Anjuere, Stebe, Hancock, Hueber: Requirement for Daxx in mature T-cell proliferation and activation. in Cell death and differentiation 2007 (PubMed)
Human Polyclonal DAXX Primary Antibody for ICC, IF - ABIN315683 : Weisbrod, Zhang, Jain, Barak, Quezado, Kebebew: Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors. in Hormones & cancer 2013 (PubMed)
Human Monoclonal DAXX Primary Antibody for ICC, IP - ABIN302079 : Símová, Klíma, Cermak, Sourková, Andera: Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane. in Apoptosis : an international journal on programmed cell death 2008 (PubMed)
Show all 5 Pubmed References
Cow (Bovine) Polyclonal DAXX Primary Antibody for IHC, IHC (p) - ABIN4304321 : Yang, Hu, Chen, Zhu, Li, Lu, Li, Dong: Necrostatin-1 protects hippocampal neurons against ischemia/reperfusion injury via the RIP3/DAXX signaling pathway in rats. in Neuroscience letters 2017 (PubMed)

More Antibodies against Death-Domain Associated Protein Interaction Partners

Human Death-Domain Associated Protein (DAXX) interaction partners

Both primary Alternative lengthening of telomeres(ALT) -positive and ATRX (show ATRX Antibodies)/DAXX-negative PanNETs are independently associated with aggressive clinicopathologic behavior and displayed reduced recurrence-free survival. In contrast, ALT activation and loss of ATRX (show ATRX Antibodies)/DAXX are both associated with better overall survival in patients with metastases
Whole-exome sequencing has identified recurrent mutations in the genes DAXX and ATRX (show ATRX Antibodies), which correlate with loss of protein expression and alternative lengthening of telomeres (ALT).ALT and DAXX/ATRX (show ATRX Antibodies) loss in PanNETs was associated with shorter disease-free survival (DFS (show FST Antibodies)) and disease-specific survival (DSS (show NR0B1 Antibodies)) and likely plays a significant role in driving metastatic disease
We propose that mutations in alpha thalassemia-mental retardation syndrome X-linked (ATRX (show ATRX Antibodies))/death-domain associated protein (DAXX) prime alternative lengthening of telomeres activation by disrupting telomeric heterochromatin.
Structural and biochemical characterization of DAXX-ATRX (show ATRX Antibodies) interaction.
Structural basis for DAXX interaction with ATRX (show ATRX Antibodies).
Given the high frequency of ATRX (show ATRX Antibodies) and DAXX mutations in cancer, these chromatin regulators likely play a key role in pathogenesis [review]
H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements.
DAXX gene plays a role in the pathogenesis of neuroendocrine pancreatic neoplasms.
The widespread dynamic nature of DAXX methylation in association with trophoblast differentiation and placenta-associated pathologies is consistent with an important role for this gene in proper placental development and function.
findings reveal a previously unappreciated cross-talk between two crucial tumor suppressor genes, MEN1 and DAXX, thought to work by independent pathways

Mouse (Murine) Death-Domain Associated Protein (DAXX) interaction partners

PML (show PML Antibodies) protein organizes heterochromatin domains where it regulates histone H3.3 (show H3F3A Antibodies) deposition by ATRX (show ATRX Antibodies) and DAXX.
data support a model in which activation of myogenic differentiation results in PML (show PML Antibodies) NB loss, chromatin reorganization and DAXX relocalization, and provides a paradigm for understanding the consequence of PML (show PML Antibodies) loss in other cellular contexts, such as during cancer development and progression
This study provides important details regarding the expression and post-translational modifications of DAXX in aging in the entire organism and provides reference data for the deregulation observed in age-associated diseases.
This is a promising novel therapeutic approach because it appears to be effective in a model producing severe injury by interfering with an array of proximal signals and effectors of the ischemic cascade, upstream of JNK (show MAPK8 Antibodies), caspases, and BIM (show BCL2L11 Antibodies) and BAX (show BAX Antibodies) activation.
Daxx and Atrx (show ATRX Antibodies) safeguard the genome by silencing repetitive elements when DNA methylation (show HELLS Antibodies) levels are low.
The protein levels of Daxx is reduced in Stella (show DPPA3 Antibodies)-null oocytes and embryos.
Daxx selectively represses IL-6 (show IL6 Antibodies) transcription through HDAC1 (show HDAC1 Antibodies)-mediated histone deacetylation
Overall, these data imply a regulatory role for Daxx in reovirus-induced apoptosis, depending on its location in the nucleus or cytoplasm.
phosphorylation of Daxx by RIP3 (show MPRIP Antibodies) comprises an important part of ischemic necrosis in rat retinal ganglion cells
DAXX is associated with regulatory regions of selected activity-regulated genes, where it promotes H3.3 loading upon membrane depolarization. DAXX loss not only affects H3.3 deposition but also impairs transcriptional induction of these genes.

Zebrafish Death-Domain Associated Protein (DAXX) interaction partners

Daxx mRNA was detected in embryonic development from 6 h to 120 h and in all 11 selected zebrafish tissues, and Daxx expression first increased and then decreased during megalocytivirus infectious spleen and kidney necrosis virus infection.

Death-Domain Associated Protein (DAXX) Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Death-Domain Associated Protein (DAXX)

death domain associated protein (DAXX) antibody
Fas death domain-associated protein (Daxx) antibody
death associated protein 3 (dap3) antibody
28S ribosomal protein S29, mitochondrial (LOC100226911) antibody
death associated protein 3 (DAP3) antibody
death-domain associated protein (Daxx) antibody
death domain associated protein (Daxx) antibody
death-associated protein 6 L homeolog (daxx.L) antibody
death-domain associated protein (daxx) antibody

BING2 antibody
DAP6 antibody
daxx antibody
EAP1 antibody
im:6905684 antibody
LOC100226911 antibody
si:dz179b20.7 antibody
wu:fd15c03 antibody

Protein level used designations for DAXX

CENP-C binding protein , ETS1-associated protein 1 , Fas-binding protein , death domain-associated protein 6 , death-associated protein 6 , fas death domain-associated protein , death-domain associated protein , 28S ribosomal protein S29, mitochondrial , death associated protein 3 , 28S ribosomal protein S29, mitochondrial-like , Fas death domain-associated protein , LOW QUALITY PROTEIN: death domain-associated protein 6 , death-associated protein 6 L homeolog , fas-binding

GENE ID	SPECIES
1616	Homo sapiens
13163	Mus musculus
559007	Danio rerio
100226911	Taeniopygia guttata
100394329	Callithrix jacchus
140926	Rattus norvegicus
474873	Canis lupus familiaris
100524813	Sus scrofa
504336	Bos taurus
100730008	Cavia porcellus
446279	Xenopus laevis
100505403	Ovis aries musimon
561006	Danio rerio

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