anti-Rabbit Prohibitin 2 antibody for Immunohistochemistry

Recommended Prohibitin 2 Antibody (supplied by: Log in to see )

Antigen
Prohibitin 2 (PHB2) Antibodies
  • bcap37
  • zgc:73150
  • wu:fc28c08
  • PHB2
  • phb2
  • ATPHB2
  • F21M11.21
  • F21M11_21
  • prohibitin 2
  • DKFZp469N1310
  • BAP
  • BCAP37
  • Bap37
  • PNAS-141
  • REA
  • p22
  • bap37
  • prohibitin2
  • xphb2
  • AU044498
  • Bcap37
  • Bap
  • Bap-37
  • Bcap27
  • prohibitin 2a
  • prohibitin 2
  • prohibitin 2 S homeolog
  • phb2a
  • PHB2
  • phb2
  • phb2.S
  • Phb2
Epitope
C-Term
21
17
10
7
7
6
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
133
65
43
11
8
7
6
5
3
2
2
2
2
1
1
1
1
Host
Rabbit
131
3
3
Clonality
Polyclonal
Conjugate
This Prohibitin 2 antibody is un-conjugated
6
6
5
5
5
4
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
110
54
49
34
18
13
13
13
5
4
3
3
2
2
1
1
Options
Supplier
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Available images

Catalog No. ABIN2783329
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.97007 ABIN2783328 IHC WB Rabbit N-Term Log in to see Polyclonal 1
1 ABIN2627248 ICC IHC IHC (p) WB Rabbit IgG AA 111-128 Log in to see Polyclonal 0
1 ABIN1926923 IF IHC IHC (p) Rabbit IgG AA 1-50 Log in to see Polyclonal 0
1 ABIN1926922 IF IHC IHC (p) IP Rabbit IgG AA 1-50 Log in to see Polyclonal 0

General

Antigen Prohibitin 2 (PHB2) Antibodies
Epitope C-Term
(21), (17), (10), (7), (7), (6), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(133), (65), (43), (11), (8), (7), (6), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(131), (3), (3)
Clonality
Polyclonal
Conjugate This Prohibitin 2 antibody is un-conjugated
(6), (6), (5), (5), (5), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(110), (54), (49), (34), (18), (13), (13), (13), (5), (4), (3), (3), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-Prohibitin 2 Antibody

Target Details Prohibitin 2 Application Details Handling References for anti-Prohibitin 2 antibody (ABIN2783329) Images
Blocking Peptide Blocking peptide for this product available: ABIN981666
Sequence KLRKIRAAQN ISKTIATSQN RIYLTADNLV LNLQDESFTR GSDSLIKGKK
Predicted Reactivity Cow: 100%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against PHB2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human PHB2
Plasmids, Primers & others

Target Details Prohibitin 2

Product Details anti-Prohibitin 2 Antibody Application Details Handling References for anti-Prohibitin 2 antibody (ABIN2783329) Images back to top
Antigen
Alternative Name PHB2 (PHB2 Antibody Abstract)
Background PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
Alias Symbols: BAP, BCAP37, Bap37, MGC117268, PNAS-141, REA, p22
Protein Interaction Partner: HUWE1, IGF1R, HDAC1, ESR1, KIAA1244, NCOR1, SUMO2, STAU1, UBC, MDM2, ASB14, ASB17, SUZ12, EED, RNF2, UPF2, ADRB2, CDK2, env, VCAM1, TEAD3, ITGA4, ILF3, FN1, ATF2, C1QBP, AFP, UBL4A, EPAS1, FMNL1, PAXIP1, MDC1, MYOD1, MEF2A, FHL2, ECT2, BRCA1, AKT1, Htt, U
Protein Size: 299
Molecular Weight 33 kDa
Gene ID 11331
NCBI Accession NM_007273, NP_009204
UniProt Q99623
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling

Application Details

Product Details anti-Prohibitin 2 Antibody Target Details Prohibitin 2 Handling References for anti-Prohibitin 2 antibody (ABIN2783329) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 299 AA

Restrictions For Research Use only

Handling

Product Details anti-Prohibitin 2 Antibody Target Details Prohibitin 2 Application Details References for anti-Prohibitin 2 antibody (ABIN2783329) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Prohibitin 2 antibody (ABIN2783329)

Product Details anti-Prohibitin 2 Antibody Target Details Prohibitin 2 Application Details Handling Images back to top
Background publications

Ross, Nagy, Kirken: "The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4699-713, 2008

Images

Product Details anti-Prohibitin 2 Antibody Target Details Prohibitin 2 Application Details Handling References for anti-Prohibitin 2 antibody (ABIN2783329) back to top
Supplier Images
Western Blotting (WB) image for anti-Prohibitin 2 (PHB2) (C-Term) antibody (ABIN2783329) WB Suggested Anti-PHB2 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cel...
Western Blotting (WB) image for anti-Prohibitin 2 (PHB2) (C-Term) antibody (ABIN2783329) WB Suggested Anti-PHB2 Antibody Titration: 1 ug/mlPositive Control: Rat tissue
Western Blotting (WB) image for anti-Prohibitin 2 (PHB2) (C-Term) antibody (ABIN2783329) WB Suggested Anti-PHB2 antibody Titration: 1 ug/mL Sample Type: Human heart
Immunohistochemistry (IHC) image for anti-Prohibitin 2 (PHB2) (C-Term) antibody (ABIN2783329) Rabbit Anti-PHB2 Antibody Formalin Fixed Paraffin Embedded Tissue: Human Adult hea...
Immunohistochemistry (IHC) image for anti-Prohibitin 2 (PHB2) (C-Term) antibody (ABIN2783329) Rabbit Anti-PHB2 Antibody Formalin Fixed Paraffin Embedded Tissue: Human heart Tiss...