anti-Mouse (Murine) AGT antibody for ELISA

Recommended AGT Antibody (supplied by: Log in to see )

Antigen
Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Antibodies
  • ANHU
  • SERPINA8
  • AI265500
  • AngI
  • AngII
  • Aogen
  • Serpina8
  • ANRT
  • Ang
  • PAT
  • wu:fb62f06
  • wu:fj87b02
  • zgc:111892
  • AGT
  • angt
  • ANGT
  • angiotensinogen
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • AGT
  • Agt
  • agt
Epitope
AA 1-477
37
16
13
11
8
8
8
5
5
5
5
4
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
225
68
62
8
2
2
2
2
2
2
1
Host
Rabbit
182
82
2
Clonality
Polyclonal
Conjugate
This AGT antibody is un-conjugated
20
14
6
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
172
104
91
47
24
22
20
14
14
11
6
4
3
2
1
1
1
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Catalog No. ABIN2000803
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN6259830 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2691419 ELISA Rabbit IgG AA 1-477 Log in to see Polyclonal 0
1 ABIN796715 ELISA Rabbit IgG Log in to see Polyclonal 0
1 ABIN6097868 ELISA IF/ICC IHC WB Rabbit IgG AA 35-285 Log in to see Polyclonal 0
1 ABIN1173619 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN2426559 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2431969 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2430999 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2426561 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2431971 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6044526 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6044744 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6045122 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6042513 ELISA Rabbit IgG Log in to see Polyclonal 0
1 ABIN6044745 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2906739 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN5702052 ELISA FACS IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1082946 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2753291 IHC ELISA WB Rabbit IgG AA 35-285 Log in to see Polyclonal 0
1 ABIN5911989 ELISA FACS IHC WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Antibodies
Epitope AA 1-477
(37), (16), (13), (11), (8), (8), (8), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(225), (68), (62), (8), (2), (2), (2), (2), (2), (2), (1)
Host Rabbit
(182), (82), (2)
Clonality
Polyclonal
Conjugate This AGT antibody is un-conjugated
(20), (14), (6), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(172), (104), (91), (47), (24), (22), (20), (14), (14), (11), (6), (4), (3), (2), (1), (1), (1)
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Product Details anti-AGT Antibody

Target Details AGT Application Details Handling Images
Specificity Mouse Angiotensinogen / SerpinA8 / AGT
Characteristics Produced in rabbits immunized with purified, recombinant Mouse Angiotensinogen / SerpinA8 / AGT (rM Angiotensinogen / SerpinA8 / AGT, ABIN2007685 P11859, Met 1-Val 477,. Angiotensinogen / SerpinA8 / AGT specific IgG was purified by Mouse Angiotensinogen / SerpinA8 / AGT affinity chromatography.
Purification purified by affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Mouse Angiotensinogen / SerpinA8 / AGT protein (ABIN2007685)
Isotype IgG
Plasmids, Primers & others

Target Details AGT

Product Details anti-AGT Antibody Application Details Handling Images back to top
Antigen
Alternative Name AGT (AGT Antibody Abstract)
Background Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essential component of the renin-angiotensin system (RAS) and a potent regulator of blood pressure. Angiotensinogen can be schematically considered to consist of a combination of an angiotensin I (Ang I) function, located at the N-terminal end, and the presence of a serpin (serine protease inhibitor) structure at the opposite end. Angiotensinogen is cleaved into three chains: Angiotensin-1 (Ang I), Angiotensin-2 (Ang II), and Angiotensin-3 (Ang III). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2. Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3, angiotensin-4. Angiotensin 1-7 is cleaved from angiotensin-2 by ACE2. Angiotensin-2 acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system. Defects in AGT are associated with susceptibility to essential hypertension and renal tubular dysgenesis (RTD). Several serpins (antithrombin, maspin, pigment epithelial-derived factor, and kallistatin) have been recently shown to exert an antiangiogenic activity, suggesting a common mechanism of endothelial cell proliferation and migration. Angiotensinogen/AGT and its renin-cleaved product, des(Ang I)AGT, are also angiogenesis inhibitors, both in vitro and in vivo at concentrations within the range of those observed in plasma. The Angiotensinogen products, that is angiotensin II and possibly angiotensin II-related products, have been found to act locally in modulating adipose tissue growth in an autocrine/paracrine manner. The transient or chronic overexpression of angiotensinogen in adipose tissue favors lipogenesis in adipocytes and leads to a 'vicious' circle whereby adipose tissue development is further increased.
UniProt P11859
Pathways JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-AGT Antibody Target Details AGT Handling Images back to top
Application Notes WB: 5-10 μg/mL
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse AGT. The detection limit for Mouse AGT is approximately 0.00245 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-AGT Antibody Target Details AGT Application Details Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

Images

Product Details anti-AGT Antibody Target Details AGT Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 1-477) antibody (ABIN2000803) anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 1-477) antibody