anti-Human Angiotensin II Type-1 Receptor antibody for Immunofluorescence

Recommended Angiotensin II Type-1 Receptor Antibody (supplied by: Log in to see )

Antigen
Angiotensin II Receptor, Type 1 (AGTR1) Antibodies
  • AG2S
  • AGTR1A
  • AGTR1B
  • AT1
  • AT1AR
  • AT1B
  • AT1BR
  • AT1R
  • AT2R1
  • AT2R1A
  • AT2R1B
  • HAT1R
  • 1810074K20Rik
  • AI551199
  • AT1a
  • Agtr-1a
  • Agtr1
  • Angtr-1a
  • XAT-1
  • agtr1-A
  • agtr1.2
  • AT1-R
  • at1
  • AGTR1
  • agtr1
  • agtr1-a
  • agtr1-b
  • xAT
  • angiotensin II receptor type 1
  • angiotensin II receptor, type 1a
  • angiotensin II receptor type 1 S homeolog
  • uncharacterized AGTR1
  • angiotensin II receptor type 1 L homeolog
  • AGTR1
  • Agtr1a
  • agtr1.S
  • Agtr1
  • agtr1.L
Reactivity
Human
115
84
77
5
5
3
3
2
2
2
2
2
1
1
Host
Rabbit
100
17
5
4
4
Clonality
Polyclonal
Conjugate
This Angiotensin II Type-1 Receptor antibody is un-conjugated
4
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
105
61
47
32
21
16
13
7
5
4
3
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN5663866
$ 452.24
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.5 ABIN6256893 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 1
14.313191 ABIN5572208 ELISA IF IHC WB Rabbit Log in to see Polyclonal 0
12.572235 ABIN2133224 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
11.313191 ABIN654078 FACS IF IHC (p) WB Rabbit Ig Fraction AA 211-240, Center Log in to see Polyclonal 0
11.313191 ABIN1535649 IF ELISA WB Rabbit IgG AA 101-150 Log in to see Polyclonal 0
4 ABIN4902858 FACS IF IHC WB Rabbit IgG Log in to see Polyclonal 0
4 ABIN5572207 IF IHC WB Rabbit Log in to see Polyclonal 0
1 ABIN2892478 IF WB Rabbit Leu143 Log in to see Polyclonal 0
1 ABIN2861333 IF IHC ELISA WB Rabbit Log in to see Polyclonal 0
1 ABIN4964880 IC IF IHC WB Rabbit IgG Center Log in to see Polyclonal 0
1 ABIN2197598 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN5539953 EIA ICC IF WB Rabbit AA 110-160 Log in to see Polyclonal 0
1 ABIN2197608 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Angiotensin II Receptor, Type 1 (AGTR1) Antibodies
Reactivity Human
(115), (84), (77), (5), (5), (3), (3), (2), (2), (2), (2), (2), (1), (1)
Host Rabbit
(100), (17), (5), (4), (4)
Clonality
Polyclonal
Conjugate This Angiotensin II Type-1 Receptor antibody is un-conjugated
(4), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(105), (61), (47), (32), (21), (16), (13), (7), (5), (4), (3), (1)
Supplier Log in to see

Product Details anti-Angiotensin II Type-1 Receptor Antibody

Target Details Angiotensin II Type-1 Receptor Application Details Handling Images
Purification Affinity purification
Immunogen A synthetic peptide of human AGTR1
Isotype IgG
Plasmids, Primers & others

Target Details Angiotensin II Type-1 Receptor

Product Details anti-Angiotensin II Type-1 Receptor Antibody Application Details Handling Images back to top
Antigen
Alternative Name AGTR1 (AGTR1 Antibody Abstract)
Background Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC gamma is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites.
Synonyms: AT1, AG2S, AT1B, AT1R, AT1AR, AT1BR, AT2R1, HAT1R, AGTR1A, AGTR1B, AT2R1A, AT2R1B
Gene ID 185
UniProt P30556
Pathways JAK-STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour

Application Details

Product Details anti-Angiotensin II Type-1 Receptor Antibody Target Details Angiotensin II Type-1 Receptor Handling Images back to top
Application Notes Recommended dilutions: WB: 1:200-1:500, IHC: 1:50-1:100, IF: 1:20-1:50, FC: 1:20-1:50
Restrictions For Research Use only

Handling

Product Details anti-Angiotensin II Type-1 Receptor Antibody Target Details Angiotensin II Type-1 Receptor Application Details Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

Images

Product Details anti-Angiotensin II Type-1 Receptor Antibody Target Details Angiotensin II Type-1 Receptor Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Angiotensin II Receptor, Type 1 (AGTR1) antibody (ABIN5663866) anti-Angiotensin II Receptor, Type 1 (AGTR1) antibody