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|Antigen||Angiotensin II Receptor, Type 1 (AGTR1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Angiotensin II Type-1 Receptor antibody is conjugated to Alexa Fluor 488 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-Angiotensin II Type-1 Receptor AntibodyTarget Details Angiotensin II Type-1 Receptor Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human AT1R|
Target Details Angiotensin II Type-1 ReceptorProduct Details anti-Angiotensin II Type-1 Receptor Antibody Application Details Handling Images back to top
|Alternative Name||Angiotensin II Type 1 Receptor (AGTR1 Antibody Abstract)|
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].
Subcellular location: Cytoplasm
Synonyms: AG2S, Agtr 1, Agtr1, Agtr1a, AGTR1B, Angiotensin II receptor type 1, Angiotensin II type 1 receptor, AT-1B, AT-1r, AT1, At1a, AT1AR, AT1B, AT1BR, AT2R1, AT2R1A, AT2R1B, HAT1R, Type 1 angiotensin II receptor, AGTR1_HUMAN, Type-1 angiotensin II receptor, Angiotensin II type-1 receptor, AT1R, Ang II, Angiotensin II receptor type 1, Angiotensin II type 1 receptor, Angiotensin receptor 1, Angiotensin receptor 1B, AT 1B, AT1, AT1R.
|Pathways||JAK-STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour|
Application DetailsProduct Details anti-Angiotensin II Type-1 Receptor Antibody Target Details Angiotensin II Type-1 Receptor Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-Angiotensin II Type-1 Receptor Antibody Target Details Angiotensin II Type-1 Receptor Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|