|Antigen||Interleukin 2 Receptor, alpha (IL2RA) Antibodies|
|Reactivity||Human, Monkey Alternatives|
|Conjugate||This CD25 antibody is conjugated to PE-Cy5 Alternatives|
Flow Cytometry (FACS)
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Product Details anti-CD25 AntibodyTarget Details CD25 Application Details Handling Images
|Specificity||This antiobdy recognizes the CD25 cell surface antigen, the low affinity receptor for IL-2. CD25 is expressed by activated lymphocytes.|
|Characteristics||Synonyms: Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, p55, TACantigen|
|Purification||Purified IgG prepared by affinity chromatography|
Target Details CD25Product Details anti-CD25 Antibody Application Details Handling Images back to top
|Alternative Name||CD25 / IL2RA (IL2RA Antibody Abstract)|
|Background||CD25 is derived from a 272 amino acid precursor to yield a 251 amino acid monomeric receptor of ~53 kDa which acts as the low affinity receptor for IL-2. CD25 associates with the IL-2 receptor β (CD122) and common γ chains (CD132) to form the high affinity IL-2R complex. CD25 is expressed by activated lymphocytes (Jackson et al. 1990, Butcher et al. 1990). Defects in CD4+/ CD25+ reglatory T cells have been implicated in the pathogenesis of autoimmune diabetes (Lindley et al. 2005) and other autoimmune conditions (Sakaguchi et al. 1995).Synonyms: IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, Interleukin-2 receptor alpha chain, TAC antigen, p55|
|Pathways||JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation|
Application DetailsProduct Details anti-CD25 Antibody Target Details CD25 Handling Images back to top
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD25 Antibody Target Details CD25 Application Details Images back to top
|Buffer||PBS, pH 7.2, 0.09 % Sodium Azide, 0.2 % BSA|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: 6 month from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containssodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled bytrained staff only.
|Expiry Date||6 months|