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|Antigen||Interleukin 13 (IL13) Antibodies|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This IL-13 antibody is un-conjugated Alternatives|
Blocking Antibody (Inhibition), ELISA, Western Blotting (WB)
Product Details anti-IL-13 AntibodyTarget Details IL-13 Application Details Handling Images
|Immunogen||IL13 antibody was raised in rabbit using highly pure recombinant murine IL-13 as the immunogen.|
|Plasmids, Primers & others|
Target Details IL-13Product Details anti-IL-13 Antibody Application Details Handling Images back to top
|Alternative Name||IL13 (IL13 Antibody Abstract)|
|Background||IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL1beta, TNF-alpha, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL13 activity inhibits the pathophysiology of asthma. Human and Mouse IL13 is cross-species reactive.|
|Molecular Weight||12.3 kDa (predicted detection band MW)|
|Pathways||JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport|
Application DetailsProduct Details anti-IL-13 Antibody Target Details IL-13 Handling Images back to top
ELISA: 0.5-2 µg/mL, Inhibition: 0.08-0.1 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL-13 Antibody Target Details IL-13 Application Details Images back to top
|Buffer||Lyophilized from PBS, pH 7.2.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|