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IL-4 Proteins

(Interleukin 4 (IL4))
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
IL-4 Protein (AA 25-153) IL-4 Protein (AA 25-153) IL-4 Protein (AA 25-153) (ABIN7274949)

IL4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

IL-4 Protein (AA 25-153) (His tag) IL-4 Protein (AA 25-153) (His tag) IL-4 Protein (AA 25-153) (His tag) (ABIN7274948)

IL4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

IL-4 Protein (AA 25-153) (His-Avi Tag,Biotin) IL-4 Protein (AA 25-153) (His-Avi Tag,Biotin) IL-4 Protein (AA 25-153) (His-Avi Tag,Biotin) (ABIN7274951)

IL4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE

IL-4 Proteins by Grade

Find IL-4 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

IL-4 Proteins by Origin

Find IL-4 Proteins for a variety of species such as anti-Human IL-4, anti-Mouse IL-4, anti-Rat IL-4. The species listed below are among those available. Click on a link to go to the corresponding products.

IL-4 Proteins by Source

Here you will find IL-4 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

IL-4 Proteins by Protein Type

Here you can find IL-4 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

IL-4 Proteins by Application

Find IL-4 Proteins validated for a specific application such as SDS, ELISA, WB, Func. Some of the available applications are listed below. Click on a link to go to the corresponding products.

IL-4 Proteins by Biological Activity

Find IL-4 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular IL-4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274949
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274948
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274951
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source CHO Cells
Validations
  • (2)
Cat. No. ABIN2018020
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source CHO Cells
Validations
  • (2)
Cat. No. ABIN2018117
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274950
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN3137668
Quantity 200 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123600
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123597
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320597
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307826
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5569918
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307825
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320599
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3081750
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our IL-4 Proteins

Huang, Yi, Hu, Du, Wang, Ye, Su, Kijlstra, Yang: "Linoleic acid inhibits in vitro function of human and murine dendritic cells, CD4+T cells and retinal pigment epithelial cells." in: Graefe's archive for clinical and experimental ophthalmology, (2020) (PubMed).

He, Wang, Su, Deng, Ye, Huang, Yuan, Aize, Li, Yang: "Decreased expression of A20 is associated with ocular Behcet's disease (BD) but not with Vogt-Koyanagi-Harada (VKH) disease." in: The British journal of ophthalmology, Vol. 102, Issue 8, pp. 1167-1172, (2019) (PubMed).

Yi, Chang, Hu, Qiu, Wang, Cao, Yuan, Su, Zhou, Wang, Kijlstra, Yang: "Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease." in: Investigative ophthalmology & visual science, Vol. 59, Issue 11, pp. 4662-4669, (2019) (PubMed).

Wang, Lin, Zeng, Ouyang, Ran, Yang, Liu: "Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells." in: Scientific reports, Vol. 7, Issue 1, pp. 8519, (2019) (PubMed).

Li, Huo, Fang, Zou, Gu, Tao, Xu: "ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM." in: Frontiers in cellular neuroscience, Vol. 12, pp. 489, (2018) (PubMed).

Wang, Mo, Xiao, An, Liu, Ba, Wu, Ran, Yang, Liu: "Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model." in: Scientific reports, Vol. 7, pp. 43322, (2018) (PubMed).

Qiu, Yu, Zhu, Ye, Deng, Su, Cao, Yuan, Kijlstra, Yang: "Hypermethylation of Interferon Regulatory Factor 8 (IRF8) Confers Risk to Vogt-Koyanagi-Harada Disease." in: Scientific reports, Vol. 7, Issue 1, pp. 1007, (2017) (PubMed).

Tao, Yang, Jia, Wan, Cheng, Lu: "Molecular cloning, recombinant expression and characterization of GMCSF from the rhesus monkey, Macaca mulatta." in: Developmental and comparative immunology, Vol. 40, Issue 1, pp. 69-77, (2013) (PubMed).

Martinez-Navio, Casanova, Pacheco, Naval-Macabuhay, Climent, Garcia, Gatell, Mallol, Gallart, Lluis, Franco: "Adenosine deaminase potentiates the generation of effector, memory, and regulatory CD4+ T cells." in: Journal of leukocyte biology, Vol. 89, Issue 1, pp. 127-36, (2011) (PubMed).

Bosco, McKenna, Firth, Sly, Holt: "A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 10, pp. 6011-21, (2009) (PubMed).

Aliases for IL-4 Proteins

interleukin 4 (IL4) Proteins
interleukin 4 (Il4) Proteins
BCGF-1 Proteins
BCGF1 Proteins
BSF-1 Proteins
BSF1 Proteins
IL-4 Proteins
Il-4 Proteins
IL2 Proteins
IL4 Proteins
Il4e12 Proteins
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