anti-Mouse (Murine) IL-6 Receptor antibody for ELISA

Recommended IL-6 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin-6 Receptor (IL6R) Antibodies
  • IL6R
  • il-6ra
  • CD126
  • IL-6R-1
  • IL-6RA
  • IL6Q
  • IL6RA
  • IL6RQ
  • gp80
  • IL6R1
  • Il6ra
  • IL-6Ralpha
  • IL-6R
  • Il6r
  • interleukin 6 receptor
  • interleukin 6 receptor, alpha
  • IL6R
  • il6r
  • Il6r
  • Il6ra
Epitope
AA 44-357
24
19
17
15
10
7
7
6
6
5
5
5
5
5
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
185
86
45
1
Host
Rabbit
131
93
45
21
1
1
1
Clonality
Polyclonal
Conjugate
This IL-6 Receptor antibody is un-conjugated
26
15
15
15
9
8
6
6
4
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
131
121
103
69
40
24
24
17
14
13
10
10
9
8
8
6
4
3
2
2
2
2
2
1
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Catalog No. ABIN2000701
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2000697 ELISA Rabbit IgG AA 44-357 Log in to see 5 1
1 ABIN2000699 ELISA Rabbit IgG AA 44-357 Log in to see Polyclonal 1
1 ABIN327368 ELISA WB Rat IgG1 Extracellular Domain Log in to see 0
1 ABIN1905202 ELISA Goat AA 246-260, Extracellular Domain Log in to see Polyclonal 0
1 ABIN2624198 ELISA WB Biotin Rabbit IgG AA 52-204 Log in to see Polyclonal 0
1 ABIN2624200 ELISA WB Biotin Rabbit IgG AA 205-347 Log in to see Polyclonal 0
1 ABIN2624203 ELISA WB FITC Rabbit IgG AA 52-204 Log in to see Polyclonal 0
1 ABIN2624207 ELISA WB FITC Rabbit IgG AA 205-347 Log in to see Polyclonal 0
1 ABIN2609959 ELISA WB Rabbit IgG AA 52-204 Log in to see Polyclonal 0
1 ABIN2609956 ELISA WB Rabbit IgG AA 205-347 Log in to see Polyclonal 0
1 ABIN1175056 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN2935540 ELISA IF/ICC IHC WB Rabbit AA 52-204 Log in to see Polyclonal 0
1 ABIN2935539 ELISA IF/ICC IHC WB Rabbit AA 205-347 Log in to see Polyclonal 0

General

Antigen Interleukin-6 Receptor (IL6R) Antibodies
Epitope AA 44-357
(24), (19), (17), (15), (10), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(185), (86), (45), (1)
Host Rabbit
(131), (93), (45), (21), (1), (1), (1)
Clonality
Polyclonal
Conjugate This IL-6 Receptor antibody is un-conjugated
(26), (15), (15), (15), (9), (8), (6), (6), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(131), (121), (103), (69), (40), (24), (24), (17), (14), (13), (10), (10), (9), (8), (8), (6), (4), (3), (2), (2), (2), (2), (2), (1)
Pubmed 1 reference available
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Product Details anti-IL-6 Receptor Antibody

Target Details IL-6 Receptor Application Details Handling References for anti-IL-6 Receptor antibody (ABIN2000701) Images
Specificity Mouse IL6RA / CD126
Characteristics Produced in rabbits immunized with purified, recombinant Mouse IL6RA / CD126 (rM IL6RA, ABIN2007611 NP_034689.2, Ile 44-Glu 357,. IL6RA specific IgG was purified by mouse IL6RA affinity chromatography.
Purification purified by affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Mouse IL6RA protein (ABIN2007611)
Isotype IgG

Target Details IL-6 Receptor

Product Details anti-IL-6 Receptor Antibody Application Details Handling References for anti-IL-6 Receptor antibody (ABIN2000701) Images back to top
Antigen
Alternative Name IL6R (IL6R Antibody Abstract)
Background Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (sIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a sIL-6R protein are able to mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signalling. Through this so-called 'trans-signalling' mechanism, IL-6 is able to stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and sIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.
NCBI Accession NP_034689.2
Pathways JAK-STAT Signaling, Autophagy, Growth Factor Binding

Application Details

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Handling References for anti-IL-6 Receptor antibody (ABIN2000701) Images back to top
Application Notes WB: 10-20 μg/mL
ELISA: 0.5-1.0 μg/mL
This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Mouse IL6RA. The detection limit for Mouse IL6RA is 0.00245 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details References for anti-IL-6 Receptor antibody (ABIN2000701) Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

References for anti-IL-6 Receptor antibody (ABIN2000701)

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling Images back to top
Background publications

Stauber, Barill, Stauber, Miller: "Isotonic dynamometry for the assessment of power and fatigue in the knee extensor muscles of females." in: Clinical physiology (Oxford, England), Vol. 20, Issue 3, pp. 225-33, 2000

Images

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling References for anti-IL-6 Receptor antibody (ABIN2000701) back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin-6 Receptor (IL6R) (AA 44-357) antibody (ABIN2000701) anti-Interleukin-6 Receptor (IL6R) (AA 44-357) antibody