anti-Horse (Equine) IL15 antibody for Western Blotting

Recommended IL15 Antibody (supplied by: Log in to see )

Antigen
Interleukin 15 (IL15) Antibodies
  • IL15
  • AI503618
  • IL-15
  • interleukin 15
  • IL15
  • Il15
Epitope
N-Term
89
12
11
7
6
5
5
5
5
3
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
239
66
26
9
7
5
4
1
1
1
1
Host
Rabbit
146
136
18
17
5
5
Clonality
Polyclonal
Conjugate
This IL15 antibody is un-conjugated
37
17
11
10
8
6
6
6
6
5
5
3
3
3
3
3
3
3
3
3
3
2
2
1
Application
Western Blotting (WB)
209
183
66
48
32
29
27
17
13
11
10
7
5
4
4
3
3
3
1
1
1
1
1
1
1
1
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Catalog No. ABIN2786287
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN464009 WB Rabbit IgG N-Term Log in to see Polyclonal

General

Antigen Interleukin 15 (IL15) Antibodies
Epitope N-Term
(89), (12), (11), (7), (6), (5), (5), (5), (5), (3), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
(239), (66), (26), (9), (7), (5), (4), (1), (1), (1), (1)
Host Rabbit
(146), (136), (18), (17), (5), (5)
Clonality
Polyclonal
Conjugate This IL15 antibody is un-conjugated
(37), (17), (11), (10), (8), (6), (6), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Application Western Blotting (WB)
(209), (183), (66), (48), (32), (29), (27), (17), (13), (11), (10), (7), (5), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-IL15 Antibody

Target Details IL15 Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN978475
Sequence RISKPHLRSI SIQCYLCLLL NSHFLTEAGI HVFILGCFSA GLPKTEANWV
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
Characteristics This is a rabbit polyclonal antibody against IL15. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human IL15

Target Details IL15

Product Details anti-IL15 Antibody Application Details Handling Images back to top
Antigen
Alternative Name IL15 (IL15 Antibody Abstract)
Background IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
Alias Symbols: IL-15, MGC9721
Protein Interaction Partner: ZNRD1, TRAF3, STAT5B, APP, IL15RA, IL2RG, IL2RB,
Protein Size: 162
Molecular Weight 13 kDa
Gene ID 3600
NCBI Accession NM_172174, NP_751914
UniProt P40933
Research Area Immunology, Innate Immunity, Cytokines
Pathways JAK-STAT Signaling, Glycosaminoglycan Metabolic Process

Application Details

Product Details anti-IL15 Antibody Target Details IL15 Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 162 AA

Restrictions For Research Use only

Handling

Product Details anti-IL15 Antibody Target Details IL15 Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-IL15 Antibody Target Details IL15 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin 15 (IL15) (N-Term) antibody (ABIN2786287) WB Suggested Anti-IL15 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...