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|Antigen||Interleukin 15 (IL15) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This IL15 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-IL15 AntibodyTarget Details IL15 Application Details Handling Images
|Specificity||IL15 antibody was raised against the N terminal of IL15|
|Immunogen||IL15 antibody was raised using the N terminal of IL15 corresponding to a region with amino acids RISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWV|
|Plasmids, Primers & others|
Target Details IL15Product Details anti-IL15 Antibody Application Details Handling Images back to top
|Alternative Name||IL15 (IL15 Antibody Abstract)|
|Background||IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.|
|Molecular Weight||13 kDa (MW of target protein)|
|Pathways||JAK-STAT Signaling, Glycosaminoglycan Metabolic Process|
Application DetailsProduct Details anti-IL15 Antibody Target Details IL15 Handling Images back to top
WB: 1 µg/mL
Optimal conditions should be determined by the investigator.
IL15 Blocking Peptide, catalog no. 33R-7982, is also available for use as a blocking control in assays to test for specificity of this IL15 antibody
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL15 Antibody Target Details IL15 Application Details Images back to top
|Reconstitution||Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IL15 antibody in PBS|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.|
ImagesProduct Details anti-IL15 Antibody Target Details IL15 Application Details Handling back to top