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|Antigen||Interleukin 2 Receptor, beta (IL2RB) Antibodies|
|Conjugate||This IL2 Receptor beta antibody is conjugated to APC Alternatives|
Flow Cytometry (FACS), Functional Studies (Func), Immunoprecipitation (IP)
Product Details anti-IL2 Receptor beta AntibodyTarget Details IL2 Receptor beta Application Details Handling Images
The mouse monoclonal antibody TU27 recognizes CD122 (IL-2R beta), a 70-75 kDa type I transmembrane glycoprotein constitutively expressed by NK cells and a T cell subset, and upregulated upon activation.
HLDA V, WS Code C050
|Immunogen||TL-Mor cell line|
|Plasmids, Primers & others|
Target Details IL2 Receptor betaProduct Details anti-IL2 Receptor beta Antibody Application Details Handling Images back to top
|Alternative Name||CD122 (IL2RB Antibody Abstract)|
|Background||CD122 (IL-2/IL-15R beta) constitutes together with CD132 (common gamma chain) and with CD25 (IL-2/IL15R alpha) the intermediate (CD122+CD132) and the high affinity (CD122+CD132+CD25) IL-2 and IL-15 receptor complex. CD122 is expressed on NK cells and lymphocytes, but at low level, unless the cell is activated. The cytoplasmic part of CD122 binds to Src-family and Jak-family kinases. The biological effect of CD122 ligation depends on whether IL-2 or IL-15 is bound to the receptor complex.|
|Pathways||JAK-STAT Signaling, Growth Factor Binding|
Application DetailsProduct Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Handling Images back to top
|Application Notes||The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests.|
The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Images back to top
|Buffer||The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.|
|Storage Comment||Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.|