anti-Mouse (Murine) IL2 Receptor beta antibody for Flow Cytometry

Recommended IL2 Receptor beta Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, beta (IL2RB) Antibodies
  • IL2RB
  • il-2rb
  • CD122
  • IL15RB
  • P70-75
  • IL2RBC
  • IL-15Rbeta
  • IL15Rbeta
  • Il-2/15Rbeta
  • Il-2Rbeta
  • p70
  • interleukin 2 receptor subunit beta
  • interleukin-2 receptor subunit beta
  • interleukin 2 receptor, beta
  • interleukin 2 receptor, beta chain
  • IL2RB
  • LOC510185
  • il2rb
  • Il2rb
Reactivity
Mouse (Murine)
224
188
98
29
10
1
1
Host
Rat
143
135
93
Clonality
Monoclonal
Conjugate
This IL2 Receptor beta antibody is conjugated to FITC
31
31
23
15
9
8
6
6
6
6
6
5
4
4
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
221
127
64
58
41
26
15
14
11
10
5
5
4
3
2
1
1
1
1
Supplier
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Catalog No. ABIN371155
$ 368.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.3628235 ABIN4900011 CyTOF FACS Rat IgG2a AA 27-240 Log in to see 130122 0
13.3628235 ABIN2662988 CyTOF FACS PE Rat IgG2b kappa Log in to see TM-beta1 6
13.3628235 ABIN2660930 FACS Biotin Rat IgG2b kappa Log in to see TM-beta1 6
13.3628235 ABIN2665533 FACS Rat IgG2b kappa Log in to see TM-beta1 5
13.3628235 ABIN2661493 FACS FITC Rat IgG2b kappa Log in to see TM-beta1 5
13.3628235 ABIN2656897 FACS APC Rat IgG2b kappa Log in to see TM-beta1 5
13.3628235 ABIN2659079 FACS PE-Cy7 Rat IgG2b kappa Log in to see TM-beta1 5
13.3628235 ABIN2662986 FACS PE Rat IgG2a kappa Log in to see 5H4 4
13.3628235 ABIN2659944 FACS PerCP-Cy5.5 Rat IgG2b kappa Log in to see TM-beta1 5
13.3628235 ABIN2660928 BR FACS IHC Biotin Rat IgG2a kappa Log in to see 5H4 4
13.3628235 ABIN2664179 FACS Rat IgG2a kappa Log in to see 5H4 5
1 ABIN2688932 FACS Biotin Rat IgG2b, kappa Log in to see TM 17
1 ABIN1177313 BR FACS IP Rat IgG2b, kappa Log in to see TM-beta 1 18
1 ABIN2688930 FACS IP Rat IgG2a, kappa Log in to see 5H4 2
1 ABIN371153 FACS APC Rat IgG2a Log in to see 5H4 4
1 ABIN371158 FACS PE Rat IgG2a Log in to see 5H4 4
1 ABIN473773 FACS FITC Rat IgG2b Log in to see TM-b1 (TM-beta1) 0
1 ABIN474666 FACS PE Rat IgG2a, kappa Log in to see 5H4 0
1 ABIN474384 FACS Biotin Rat IgG2b Log in to see TM-b1 (TM-beta1) 0
1 ABIN474418 FACS Biotin Rat IgG2a, kappa Log in to see 5H4 0

General

Antigen Interleukin 2 Receptor, beta (IL2RB) Antibodies
Reactivity Mouse (Murine)
(224), (188), (98), (29), (10), (1), (1)
Host Rat
(143), (135), (93)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2 Receptor beta antibody is conjugated to FITC
(31), (31), (23), (15), (9), (8), (6), (6), (6), (6), (6), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(221), (127), (64), (58), (41), (26), (15), (14), (11), (10), (5), (5), (4), (3), (2), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-IL2 Receptor beta Antibody

Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta antibody (ABIN371155) Images
Specificity This antibody recognises beta chain (Mr. 90-100 kDa) of the IL-2 Receptor. It does not block IL-2 binding. (Ref.1)
Characteristics Synonyms: Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL2 Receptor beta, P70-75
Immunogen Rat myeloma YB2/0 transfected with truncated mouse IL-2RB cDNA. (Ref. 1)
Clone 5H4
Isotype IgG2a
Plasmids, Primers & others

Target Details IL2 Receptor beta

Product Details anti-IL2 Receptor beta Antibody Application Details Handling References for anti-IL2 Receptor beta antibody (ABIN371155) Images back to top
Antigen
Alternative Name CD122 / IL2RB (IL2RB Antibody Abstract)
Background The IL-2 receptor is a complex of three distinct polypeptide chains: (i) the alpha chain which binds IL-2 with low affinity, (ii) the beta chain that binds IL-2 with high affinity, and (ii) the common gamma chain (gc) that does not bind IL-2. (Ref.2) The high affinity receptor complex is an alpha/beta/gamma heterotrimer with a Kd of 1.3 x 10e-11 M. (Ref.2) In mouse spleen, CD122 is expresed on ~30 % of CD8+ cells and all NK cells, but < 1 % of B cells and CD4+ T lymphocytes. In the thymus, its expression is confined to CD4-CD8+ single positive and CD4-CD8- double negative cells. (Ref.4) Cytoplasmic regions of the IL-2R beta chain are involved in IL-2-mediated cellular signaling and, via the interaction of IL-2 and its receptor complex, may be involved in the generation and differentiation of T lymphocytes. (Ref.1,4)Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
Gene ID 16185
UniProt P16297
Pathways JAK-STAT Signaling, Growth Factor Binding

Application Details

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Handling References for anti-IL2 Receptor beta antibody (ABIN371155) Images back to top
Application Notes Flow Cytometry: < / = 1 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details References for anti-IL2 Receptor beta antibody (ABIN371155) Images back to top
Concentration 0.5 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-IL2 Receptor beta antibody (ABIN371155)

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling Images back to top
Background publications

Malek, Furse, Fleming, Fadell, He: "Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 15, Issue 5, pp. 447-54, 1995

Minami, Kono, Miyazaki, Taniguchi: "The IL-2 receptor complex: its structure, function, and target genes." in: Annual review of immunology, Vol. 11, pp. 245-68, 1993

Taniguchi, Minami: "The IL-2/IL-2 receptor system: a current overview." in: Cell, Vol. 73, Issue 1, pp. 5-8, 1993

Tanaka, Tsudo, Karasuyama, Kitamura, Kono, Hatakeyama, Taniguchi, Miyasaka: "A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL-4 cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 7, pp. 2222-8, 1991

Images

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta antibody (ABIN371155) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Interleukin 2 Receptor, beta (IL2RB) antibody (FITC) (ABIN371155) anti-Interleukin 2 Receptor, beta (IL2RB) antibody (FITC)